- Spread of OXA-48-encoding plasmid in Turkey and beyond.
Spread of OXA-48-encoding plasmid in Turkey and beyond.
Antimicrobial agents and chemotherapy (2010-01-21)
Amélie Carrër, Laurent Poirel, Mesut Yilmaz, Ozay Arikan Akan, Cilli Feriha, Gaëlle Cuzon, Ghassan Matar, Patrick Honderlick, Patrice Nordmann
PMID20086157
RESUMEN
Eighteen carbapenem-resistant, OXA-48-positive enterobacterial isolates recovered from Turkey, Lebanon, Egypt, France, and Belgium were analyzed. In most isolates, similar 70-kb plasmids carrying the carbapenemase gene bla(OXA-48) were identified. That gene was located within either transposon Tn1999 or transposon Tn1999.2, which was always inserted within the same gene. This work highlights the current plasmid-mediated dissemination of the OXA-48 carbapenemase worldwide.
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