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SAB4500369

Sigma-Aldrich

Anti-Collagen IV antibody produced in rabbit

affinity isolated antibody

Sinónimos:

Arresten, COL4A1, Collagen α-1(IV) chain

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

En este momento no podemos mostrarle ni los precios ni la disponibilidad

biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 160 kDa

species reactivity

human, mouse

concentration

~1 mg/mL

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Este artículo
SAB4200873SAB4200872SAB4200875
species reactivity

viral

species reactivity

viral

species reactivity

viral

species reactivity

viral

technique(s)

ELISA: 1/25-1/200 using 2 μg/mL SARS-CoV-2 RBD (Cat. No. SAE1000) for coating and 2 μg/ml ACE2-Biotin (Cat. No. SAE0171) for competition ((Neutralizing ELISA)), indirect ELISA: 1/2000-1/4000 using 2 μg/mL SARS-CoV-2 Spike RBD (Cat. No. SAE1000) for coating, immunoblotting: 1:2000-1:4000 using SARS-CoV-2 Spike RBD (Cat. No. SAE1000) for coating.

technique(s)

immunoblotting: 1:2000-1:4000 using SARS-CoV-2 Spike RBD (Cat. No. SAE1000) for coating., indirect ELISA: 1/2000-1/4000 using 2 μg/mL SARS-CoV-2 Spike RBD (Cat. No. SAE1000) for coating

technique(s)

immunoblotting: 1:1000-1:2000 using SARS-CoV-2 Spike RBD (Cat. No. SAE1000) for coating., indirect ELISA: 1/2000-1/4000 using 2 μg/mL SARS-CoV-2 Spike RBD (Cat. No. SAE1000) for coating.

technique(s)

ELISA: 0.25-0.5 μg/mL using SARS-CoV-2 RBD (Cat. No. SAE1000) for coating, immunoblotting: 0.1-0.2 μg/mL using SARS-CoV-2 RBD (Cat. No. SAE1000)

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

form

liquid

form

liquid

form

liquid

form

liquid

General description

Anti-Collagen IV Antibody detects endogenous levels of total Collagen IV protein.
COL4A1 (collagen type IV alpha 1 chain) belongs to the collagen family. It has an N-terminal 7S domain, a C-terminal globular domain (NC1), and the central triple helical part with short interruptions of the Gly-X-Y repeats. It is an important constituent of type IV collagen in the basement membrane. The COL4A1 gene is located on human chromosome 13q34.

Immunogen

The antiserum was produced against synthesized peptide derived from human Collagen IV.

Immunogen Range: 11-60

Application

Anti-Collagen IV, N-Terminal antibody has been used in histology analysis, immunofluorescence microscopy and immunostaining.

Biochem/physiol Actions

COL4A1 (collagen type IV α 1 chain) related disorder is associated with pulmonary complication. This gene is a major constituent required in basal membrane stability. Mutations in COL4A1 result in familial porencephaly, infantile hemiplegia, cerebral small vessel disease (CSVD) and hemorrhagic stroke.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable


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