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Merck
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Key Documents

486R-1

Sigma-Aldrich

Somatostatin Receptor 2A (EP149) Rabbit Monoclonal Primary Antibody

Sinónimos:

SSTR2A

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About This Item

UNSPSC Code:
41116161

biological source

rabbit

Quality Level

500

conjugate

unconjugated

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

EP149

description

For In Vitro Diagnostic Use in Select Regions

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL (concentrate (486R-14))
vial of 0.1 mL (concentrate (486R-14-RUO) Research Use Only)
vial of 0.5 mL (concentrate (486R-15))
vial of 1.0 mL (concentrate (486R-16))
vial of 1.0 mL (concentrate (486R-16-RUO) Research Use Only)
vial of 1.0 mL (pre-dilute (486R-17-RUO) Research Use Only)
vial of 1.0 mL (pre-dilute ready-to-use (486R-17))
vial of 7.0 mL (pre-dilute ready-to-use (486R-18))
vial of 7.0 mL (pre-dilute ready-to-use (486R-18-RUO) Research Use Only)

manufacturer/tradename

Cell Marque™

technique(s)

immunohistochemistry: suitable (formalin-fixed, paraffin-embedded sections 1:25-1:100 (concentrated))

isotype

IgG

control

lymph node, pancreas, (meningioma)

shipped in

wet ice

storage temp.

2-8°C

visualization

cytoplasmic (
), membranous

General description

Somatostatin Receptor 2A (SSTR2A) is a protein highly expressed in pancreas binding somatostatin and inhibiting pancreatic enzyme secretion. SSTR2A is used as a marker for identifying meningioma from other spindle-cell tumors such as solitary fibrous tumor. SSTR2A is more frequently expressed in higher grade meningiomas and associated to its microvessel proliferation. SSTR2A has demonstrated utility as a diagnostic marker for follicular dendritic cell sarcomas and some other related tumors.

Quality

United States - IVD
Canada - RUO
European Union - IVD
Japan - RUO

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Preparation Note

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Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Legal Information

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 2

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Camille Boulagnon-Rombi et al.
Journal of neuropathology and experimental neurology, 76(4), 289-298 (2017-03-25)
The differential diagnosis between meningioma and others tumors can be challenging. This study aimed to evaluate different immunohistochemical markers for the differential diagnosis between meningioma and their morphological mimics. Immunohistochemistry was performed on tissue microarray with antiepithelial membrane antigen (EMA)
Balrik Kailey et al.
American journal of physiology. Endocrinology and metabolism, 303(9), E1107-E1116 (2012-08-31)
Somatostatin-14 (SST) inhibits insulin and glucagon secretion by activating G protein-coupled somatostatin receptors (SSTRs), of which five isoforms exist (SSTR1-5). In mice, the effects on pancreatic β-cells are mediated by SSTR5, whereas α-cells express SSTR2. In both cell types, SSTR

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