P-038

(±)-Phenylpropanolamine hydrochloride solution

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant^®

• Sinónimos: DL-Norephedrine hydrochloride, Norephedrine hydrochloride, (±)-Phenylpropanolamine hydrochloride, erythro-2-Amino-1-phenyl-1-propanol hydrochloride, DL-erythro-2-Amino-1-phenyl-1-propanol hydrochloride, DL-Phenylpropanolamine hydrochloride
• Fórmula lineal: C₆H₅CH(OH)CH(NH₂)CH₃ · HCl
• Número de CAS: 154-41-6
• Peso molecular: 187.67
• Beilstein/REAXYS Number: 3914299
• EC Number: 200-659-6
• MDL number: MFCD00013019
• UNSPSC Code: 41116107
• PubChem Substance ID: 329820034
• NACRES: NA.24

Propiedades

• grade: certified reference material
• form: liquid
• feature: Snap-N-Spike^®/Snap-N-Shoot^®
• packaging: ampule of 1 mL
• manufacturer/tradename: Cerilliant^®
• concentration: 1.0 mg/mL in methanol (as free base)
• technique(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• mp: 194-196 °C (lit.)
• application(s): clinical testing
• format: single component solution
• storage temp.: −20°C
• SMILES string: Cl.C[C@@H](N)[C@@H](O)c1ccccc1
• InChI: 1S/C9H13NO.ClH/c1-7(10)9(11)8-5-3-2-4-6-8;/h2-7,9,11H,10H2,1H3;1H/t7-,9-;/m1./s1
• InChI key: DYWNLSQWJMTVGJ-PRCZDLBKSA-N

Descripción

General description

Phenylpropanolamine, also known as Norephedrine, is a stimulant, decongestant, and anorectic drug commonly used in many prescription and over-the-counter cold and cough formulations. The drug is often abused illicitly for its psychoactive and stimulant effects. This Certified Spiking Solution^® is applicable for use in many LC-MS/MS or GC/MS applications from clinical chemistry and forensic analysis to urine drug testing.

Application

• The effects of drug-drug interaction on linezolid pharmacokinetics: A systematic review: This review assesses the interaction of various drugs with linezolid, where (±)-Phenylpropanolamine hydrochloride serves as a reference compound. It provides valuable data on the stability and interaction of pharmaceutical intermediates, highlighting the importance of (±)-Phenylpropanolamine hydrochloride in developing safer drug therapies (Xu et al., 2024).

Biochem/physiol Actions

Mixed-acting sympathomimetic amine.

Recommended products

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Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• pictograms: GHS02,GHS06,GHS08
• signalword: Danger
• hcodes: H225,H301 + H311 + H331,H370
• pcodes: P210 - P260 - P280 - P301 + P310 - P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 1
• flash_point_f: 49.5 °F - closed cup
• flash_point_c: 9.7 °C - closed cup