XPC
xeroderma pigmentosum, complementation group C
Sinónimos:
RAD4, XP3, XPCC
Especie:
Human XPC (7508), Mouse Xpc (22591), Rat Xpc (312560), Zebrafish xpc (541386), dog XPC (476521), chicken XPC (416039), domestic cat XPC (101080440), Horse XPC (100050424), naked mole-rat Xpc (101707002), Domestic Rabbit XPC (100346279) ...Más
ID UniProtKB:
ID del gen:
- Human(7508) Summary: This gene encodes a component of the nucleotide excision repair (NER) pathway. There are multiple components involved in the NER pathway, including Xeroderma pigmentosum (XP) A-G and V, Cockayne syndrome (CS) A and B, and trichothiodystrophy (TTD) group A, etc. This component, XPC, plays an important role in the early steps of global genome NER, especially in damage recognition, open complex formation, and repair protein complex formation. Mutations in this gene or some other NER components result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2009]
- Mouse(22591) xeroderma pigmentosum, complementation group C
- Rat(312560) xeroderma pigmentosum, complementation group C
- Zebrafish(541386) xeroderma pigmentosum, complementation group C
- dog(476521) xeroderma pigmentosum, complementation group C
- chicken(416039) xeroderma pigmentosum, complementation group C
- domestic cat(101080440) xeroderma pigmentosum, complementation group C
- Horse(100050424) xeroderma pigmentosum, complementation group C
- naked mole-rat(101707002) xeroderma pigmentosum, complementation group C
- Domestic Rabbit(100346279) xeroderma pigmentosum, complementation group C
- domestic guinea pig(100719007) xeroderma pigmentosum, complementation group C
- cow(524274) xeroderma pigmentosum, complementation group C
- sheep(101109650) xeroderma pigmentosum, complementation group C
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Monoclonal Anti-XPC antibody produced in mouse, ,
Reactividad de especies
human, mouse
Aplicación
immunocytochemistry
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-XPC (C-terminal) antibody produced in rabbit, ~1 mg/mL, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
human
Aplicación
immunofluorescence
western blot
western blot
Anti-XPC antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-XPC antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunofluorescence
Anti-XPC antibody produced in rabbit, ,
Reactividad de especies
human
Aplicación
immunocytochemistry
immunofluorescence
immunoprecipitation (IP)
western blot
immunofluorescence
immunoprecipitation (IP)
western blot