XIAP
X-linked inhibitor of apoptosis
Sinónimos:
API3, BIRC4, IAP-3, ILP1, MIHA, XLP2, hIAP-3, hIAP3
Especie:
Human XIAP (331), Mouse Xiap (11798), Rat Xiap (63879), Zebrafish xiap (373108), domestic cat XIAP (101090594), Horse XIAP (100060870), dog XIAP (442989), chicken XIAP (395280), domestic guinea pig Xiap (100715778), naked mole-rat Xiap (101715865) ...Más
ID UniProtKB:
ID del gen:
- Human(331) Summary: This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11.[provided by RefSeq, Feb 2011]
- Mouse(11798) X-linked inhibitor of apoptosis
- Rat(63879) X-linked inhibitor of apoptosis
- Zebrafish(373108) X-linked inhibitor of apoptosis
- domestic cat(101090594) X-linked inhibitor of apoptosis
- Horse(100060870) X-linked inhibitor of apoptosis
- dog(442989) X-linked inhibitor of apoptosis
- chicken(395280) X-linked inhibitor of apoptosis
- domestic guinea pig(100715778) X-linked inhibitor of apoptosis
- naked mole-rat(101715865) X-linked inhibitor of apoptosis
- Domestic Rabbit(100328700) X-linked inhibitor of apoptosis
- cow(281647) X-linked inhibitor of apoptosis
- sheep(101116381) X-linked inhibitor of apoptosis
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ELISA
Small Molecule - Antagonist
Referencia del producto
Descripción
Especie
Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-XIAP antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-XIAP Antibody, clone 3H4 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human, monkey, rat
Aplicación
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Anti-phospho-XIAP (pSer87) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human
Aplicación
western blot
[KO Validated]Anti-XIAP Antibody, clone 5S5Q7, Rabbit Monoclonal, ,
Reactividad de especies
human, rat
Aplicación
immunoprecipitation (IP)
western blot
western blot
Anti-XIAP antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Proteins
Referencia del producto
Descripción
Especie
XIAP Active human, recombinant, expressed in baculovirus infected insect cells, ≥65% (SDS-PAGE),
Especie
human
XIAP, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Especie
human