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Merck

TUBA4A

tubulin, alpha 4a

Sinónimos:
H2-ALPHA, TUBA1
Especie:
ID UniProtKB:
ID del gen:
  • Human(7277) Summary: Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulin. The genes encoding these microtubule constituents are part of the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes and they are highly conserved among and between species. This gene encodes an alpha tubulin that is a highly conserved homolog of a rat testis-specific alpha tubulin. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2013]
  • Mouse(22145) tubulin, alpha 4A
  • Rat(316531) tubulin, alpha 4A
  • chicken(418166) tubulin, alpha 4a
  • domestic cat(101095277) tubulin, alpha 4a
  • Horse(100059249) tubulin, alpha 4a
  • dog(478918) tubulin, alpha 4a
  • cow(777775) tubulin, alpha 4a
  • sheep(443104) tubulin, alpha 4a
  • sheep(100302357) tubulin, alpha 4a
  • domestic guinea pig(100734500) tubulin, alpha 4a
  • naked mole-rat(101720265) tubulin, alpha 4a

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-α-Tubulin Antibody, clone 3P2D9, Rabbit Monoclonal, ,
Reactividad de especies
human, rat
Aplicación
immunofluorescence
immunohistochemistry

immunoprecipitation (IP)

western blot
Monoclonal Anti-Tubulin, Tyrosine antibody produced in mouse, clone TUB-1A2, ascites fluid,
Reactividad de especies
animal, human, plant
Aplicación
immunofluorescence
microarray

western blot
Anticuerpo anti-tubulina acetilada, monoclonal de ratón antibody produced in mouse, clone 6-11B-1, purified from hybridoma cell culture,
Reactividad de especies
bovine, chicken, frog, hamster, human, invertebrates, monkey, mouse, pig, plant, rat
Aplicación
dot blot
electron microscopy

immunohistochemistry

radioimmunoassay

western blot
Anti-α-tubulina monoclonal antibody produced in mouse, ascites fluid, clone B-5-1-2,
Reactividad de especies
chlamydomonas, african green monkey, bovine, chicken, human, kangaroo rat, mouse, rat, sea urchin
Aplicación
immunofluorescence
radioimmunoassay

western blot
Anti-α-tubulina monoclonal antibody produced in mouse, clone DM1A, ascites fluid,
Reactividad de especies
amphibian, bovine, chicken, fungi, human, mouse, rat, yeast
Aplicación
immunofluorescence
western blot

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
Taxol, phyproof® Reference Substance,
Especie
human
Vinblastine sulfate, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Colchicina, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Paclitaxel, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Docetaxel, purum, ≥97.0% (HPLC),
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human TUBA4A,
Especie
human
MISSION® esiRNA, targeting mouse Tuba4a,
Especie
mouse