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MilliporeSigma

TLR9

toll-like receptor 9

Sinónimos:
CD289
Especie:
Human TLR9 (54106), Mouse Tlr9 (81897), Rat Tlr9 (338457), Zebrafish tlr9 (403128), domestic cat TLR9 (493839), Horse TLR9 (100009693), dog TLR9 (403502), cow TLR9 (282602), sheep TLR9 (494547), Goat TLR9 (100860819)
ID UniProtKB:
Q9NR96, B3Y661, D1CS56, Q6UVZ2, Q9HD68, Q9HD69, Q9HD70, Q9NYC2
ID del gen:
  • Human(54106) Summary: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is preferentially expressed in immune cell rich tissues, such as spleen, lymph node, bone marrow and peripheral blood leukocytes. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response. [provided by RefSeq, Jul 2008]
  • Mouse(81897) toll-like receptor 9
  • Rat(338457) toll-like receptor 9
  • Zebrafish(403128) toll-like receptor 9
  • domestic cat(493839) toll-like receptor 9
  • Horse(100009693) toll-like receptor 9
  • dog(403502) toll-like receptor 9
  • cow(282602) toll-like receptor 9
  • sheep(494547) toll-like receptor 9
  • Goat(100860819) toll-like receptor 9
  • naked mole-rat(101715478) toll-like receptor 9

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Small Molecule - Antagonist

Referencia del producto
Descripción
Especie
H0915
Sulfato de hidroxicloroquina, ≥98% (HPLC), powder,
Especie
human
BP1101
Sulfato de hidroxicloroquina, British Pharmacopoeia (BP) Reference Standard,
Especie
human
TMT00427
2-((4-(7-Chloroquinolin-4-ylamino)pentyl)(ethyl)amino)ethanol, ,
Especie
human
BP1100
Sulfato de hidroxicloroquina, British Pharmacopoeia (BP) Reference Standard,
Especie
human
PHR1782
Sulfato de hidroxicloroquina, Pharmaceutical Secondary Standard; Certified Reference Material,
Especie
human

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
SAB3500313
Anti-TLR9 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
human, mouse
Aplicación
ELISA
immunofluorescence
immunohistochemistry
western blot
ZRB3163
Anti-TLR9/CD289 Antibody, clone 2L12 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human, monkey, mouse, primate
Aplicación
affinity binding assay
flow cytometry
immunohistochemistry
western blot

esiRNA

Referencia del producto
Descripción
Especie
EHU095981
MISSION® esiRNA, targeting human TWF2, RP11-330H6.5,
Especie
human
EHU228341
MISSION® esiRNA, targeting human TLR9, RP11-330H6.5,
Especie
human