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Merck

SLC22A12

solute carrier family 22 (organic anion/urate transporter), member 12

Sinónimos:
OAT4L, RST, URAT1
Especie:
ID UniProtKB:
ID del gen:
  • Human(116085) Summary: The protein encoded by this gene is a member of the organic anion transporter (OAT) family, and it acts as a urate transporter to regulate urate levels in blood. This protein is an integral membrane protein primarily found in epithelial cells of the proximal tubule of the kidney. An elevated level of serum urate, hyperuricemia, is associated with increased incidences of gout, and mutations in this gene cause renal hypouricemia type 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
  • Mouse(20521) solute carrier family 22 (organic anion/cation transporter), member 12
  • Rat(365398) solute carrier family 22 (organic anion/urate transporter), member 12
  • Horse(100055832) solute carrier family 22 (organic anion/urate transporter), member 12
  • dog(483761) solute carrier family 22 (organic anion/urate transporter), member 12
  • domestic cat(101100592) solute carrier family 22 (organic anion/urate transporter), member 12
  • domestic guinea pig(100721051) solute carrier family 22 (organic anion/urate transporter), member 12
  • naked mole-rat(101714998) solute carrier family 22 (organic anion/urate transporter), member 12
  • cow(526067) solute carrier family 22 (organic anion/urate transporter), member 12
  • sheep(101117630) solute carrier family 22 (organic anion/urate transporter), member 12

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-SLC22A12 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
Lesinurad, ≥98% (HPLC),
Especie
human
(±)-Sulfinpyrazone, analytical standard,
Especie
human
Benzbromarone, European Pharmacopoeia (EP) Reference Standard,
Especie
human
Benzbromarone, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland,
Especie
human
Sulfinpyrazone, European Pharmacopoeia (EP) Reference Standard,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human SLC22A12,
Especie
human