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Merck

SDHD

succinate dehydrogenase complex, subunit D, integral membrane protein

Sinónimos:
CBT1, CII-4, CWS3, PGL, PGL1, QPs3, SDH4, cybS
Especie:
ID UniProtKB:
ID del gen:
  • Human(6392) Summary: This gene encodes a member of complex II of the respiratory chain, which is responsible for the oxidation of succinate. The encoded protein is one of two integral membrane proteins anchoring the complex to the matrix side of the mitochondrial inner membrane. Mutations in this gene are associated with the formation of tumors, including hereditary paraganglioma. Transmission of disease occurs almost exclusively through the paternal allele, suggesting that this locus may be maternally imprinted. There are pseudogenes for this gene on chromosomes 1, 2, 3, 7, and 18. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2013]
  • Mouse(66925) succinate dehydrogenase complex, subunit D, integral membrane protein
  • Rat(363061) succinate dehydrogenase complex, subunit D, integral membrane protein
  • chicken(419793) succinate dehydrogenase complex, subunit D, integral membrane protein
  • domestic cat(101095280) succinate dehydrogenase complex, subunit D, integral membrane protein
  • dog(479438) succinate dehydrogenase complex, subunit D, integral membrane protein
  • cow(281481) succinate dehydrogenase complex, subunit D, integral membrane protein
  • sheep(101111485) succinate dehydrogenase complex, subunit D, integral membrane protein
  • Goat(100860881) succinate dehydrogenase complex, subunit D, integral membrane protein
  • naked mole-rat(101702014) succinate dehydrogenase complex, subunit D, integral membrane protein
  • domestic guinea pig(100734731) succinate dehydrogenase complex, subunit D, integral membrane protein

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-SDHD antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Anti-SDHD antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
immunocytochemistry

immunofluorescence

western blot
Anti-SDHD/CybS Antibody, clone 1F5-H2L2 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
bovine, goat, human, monkey, mouse, sheep
Aplicación
flow cytometry
immunocytochemistry

immunohistochemistry

western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human SDHD,
Especie
human
MISSION® esiRNA, targeting mouse Sdhd,
Especie
mouse