RAD51
RAD51 recombinase
Sinónimos:
BRCC5, HRAD51, HsRad51, HsT16930, MRMV2, RAD51A, RECA
Especie:
Human RAD51 (5888), Mouse Rad51 (19361), Rat Rad51 (499870), cow RAD51 (514749), sheep RAD51 (101109275), Domestic Rabbit RAD51 (100008661), naked mole-rat Rad51 (101715048), domestic guinea pig Rad51 (100716391), Thale Cress RAD51 (832208), chicken RAD51 (396086) ...Más
ID UniProtKB:
ID del gen:
- Human(5888) Summary: The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009]
- Mouse(19361) RAD51 homolog
- Rat(499870) RAD51 recombinase
- cow(514749) RAD51 homolog (S. cerevisiae)
- sheep(101109275) RAD51 homolog (S. cerevisiae)
- Domestic Rabbit(100008661) RAD51 homolog (S. cerevisiae)
- naked mole-rat(101715048) RAD51 homolog (S. cerevisiae)
- domestic guinea pig(100716391) RAD51 homolog (S. cerevisiae)
- Thale Cress(832208) DNA repair protein RAD51-like 1
- chicken(396086) RAD51 homolog (S. cerevisiae)
- dog(403568) RAD51 homolog (S. cerevisiae)
- domestic cat(101089015) RAD51 homolog (S. cerevisiae)
- Zebrafish(406487) RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-RAD51 Antibody, clone 1M8 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human, mouse, rat
Aplicación
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Anti-RAD51 antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
western blot
Anti-Rad51 Antibody, clone 5S9B0, Rabbit Monoclonal, ,
Reactividad de especies
human, rat
Aplicación
ChIP
western blot
western blot
Proteins
Referencia del producto
Descripción
Especie
esiRNA
Referencia del producto
Descripción
Especie