RAD50
RAD50 homolog (S. cerevisiae)
Sinónimos:
NBSLD, RAD502, hRad50
Especie:
Human RAD50 (10111), Mouse Rad50 (19360), Rat Rad50 (64012), fruit fly rad50 (37564), Thale Cress RAD50 (817756), Horse RAD50 (100063198), domestic cat RAD50 (101095875), dog RAD50 (474674), chicken RAD50 (416329), Zebrafish rad50 (553029) ...Más
ID UniProtKB:
ID del gen:
- Human(10111) Summary: The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein, cooperating with its partners, is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination. Knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability. Mutations in this gene are the cause of Nijmegen breakage syndrome-like disorder.[provided by RefSeq, Apr 2010]
- Mouse(19360) RAD50 homolog (S. cerevisiae)
- Rat(64012) RAD50 homolog (S. cerevisiae)
- fruit fly(37564) CG6339 gene product from transcript CG6339-RE
- Thale Cress(817756) DNA repair protein RAD50
- Horse(100063198) RAD50 homolog (S. cerevisiae)
- domestic cat(101095875) RAD50 homolog (S. cerevisiae)
- dog(474674) RAD50 homolog (S. cerevisiae)
- chicken(416329) RAD50 homolog (S. cerevisiae)
- Zebrafish(553029) RAD50 homolog (S. cerevisiae)
- domestic guinea pig(100719847) RAD50 homolog (S. cerevisiae)
- naked mole-rat(101719180) RAD50 homolog (S. cerevisiae)
- Domestic Rabbit(100328725) RAD50 homolog (S. cerevisiae)
- cow(788127) RAD50 homolog (S. cerevisiae)
- sheep(101123035) RAD50 homolog (S. cerevisiae)
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Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-RAD50 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-Rad50 Antibody, clone 5M2K10, Rabbit Monoclonal, ,
Reactividad de especies
human, rat
Aplicación
immunoprecipitation (IP)
western blot
western blot