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MilliporeSigma

PRG4

proteoglycan 4

Sinónimos:
CACP, HAPO, JCAP, MSF, SZP, bG174L6.2
Especie:
Human PRG4 (23572), Human PRG4 (10216), Mouse Prg4 (96875), Rat Prg4 (289104), chicken PRG4 (768493), Horse PRG4 (100034016), domestic cat PRG4 (101085684), dog PRG4 (664716), cow PRG4 (280867), sheep PRG4 (100294585) ...Más
ID UniProtKB:
Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49
ID del gen:
  • Human(23572) Summary: The protein encoded by this gene is a large proteoglycan specifically synthesized by chondrocytes located at the surface of articular cartilage, and also by some synovial lining cells. This protein contains both chondroitin sulfate and keratan sulfate glycosaminoglycans. It functions as a boundary lubricant at the cartilage surface and contributes to the elastic absorption and energy dissipation of synovial fluid. Mutations in this gene result in camptodactyly-arthropathy-coxa vara-pericarditis syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Human(10216) Summary: The protein encoded by this gene is a large proteoglycan specifically synthesized by chondrocytes located at the surface of articular cartilage, and also by some synovial lining cells. This protein contains both chondroitin sulfate and keratan sulfate glycosaminoglycans. It functions as a boundary lubricant at the cartilage surface and contributes to the elastic absorption and energy dissipation of synovial fluid. Mutations in this gene result in camptodactyly-arthropathy-coxa vara-pericarditis syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(96875) proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein)
  • Rat(289104) proteoglycan 4
  • chicken(768493) proteoglycan 4
  • Horse(100034016) proteoglycan 4
  • domestic cat(101085684) proteoglycan 4
  • dog(664716) proteoglycan 4
  • cow(280867) proteoglycan 4
  • sheep(100294585) proteoglycan 4
  • sheep(101110076) proteoglycan 4
  • naked mole-rat(101697808) proteoglycan 4
  • Domestic Rabbit(100328909) proteoglycan 4
  • domestic guinea pig(100716004) proteoglycan 4

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
ZRB1643
Anti-Lubricin/PRG4 Antibody, clone 1C20 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human, mouse, rat
Aplicación
affinity binding assay
immunohistochemistry
western blot
ZMS1077
Anti-Lubricin/PRG4 Antibody, clone 9G3 ZooMAb® Mouse Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human, rat
Aplicación
immunofluorescence
immunohistochemistry
western blot

Proteins

Referencia del producto
Descripción
Especie
P5864
Proteoglycan from bovine nasal septum, chromatographically purified,
Especie
cow

esiRNA

Referencia del producto
Descripción
Especie
EMU215631
MISSION® esiRNA, targeting mouse Prg4,
Especie
mouse
EHU110221
MISSION® esiRNA, targeting human PRG4,
Especie
human