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Merck

PEG10

paternally expressed 10

Sinónimos:
EDR, HB-1, MEF3L, Mar2, Mart2, RGAG3
Especie:
ID UniProtKB:
ID del gen:
  • Human(23089) Summary: This is a paternally expressed imprinted gene that encodes transcripts containing two overlapping open reading frames (ORFs), RF1 and RF1/RF2, as well as retroviral-like slippage and pseudoknot elements, which can induce a -1 nucleotide frame-shift. ORF1 encodes a shorter isoform with a CCHC-type zinc finger motif containing a sequence characteristic of gag proteins of most retroviruses and some retrotransposons. The longer isoform is the result of -1 translational frame-shifting leading to translation of a gag/pol-like protein combining RF1 and RF2. It contains the active-site consensus sequence of the protease domain of pol proteins. Additional isoforms resulting from alternatively spliced transcript variants, as well as from use of upstream non-AUG (CUG) start codon, have been reported for this gene. Increased expression of this gene is associated with hepatocellular carcinomas. [provided by RefSeq, May 2010]
  • Mouse(170676) paternally expressed 10
  • Rat(678843) paternally expressed 10
  • domestic guinea pig(100720271) paternally expressed 10
  • naked mole-rat(101724514) paternally expressed 10
  • cow(618138) paternally expressed 10
  • sheep(100359412) paternally expressed 10
  • dog(482307) paternally expressed 10
  • Horse(100062501) paternally expressed 10
  • domestic cat(101094251) paternally expressed 10

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-PEG10 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Anti-PEG10 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry