NRG3
neuregulin 3
Sinónimos:
HRG3, pro-NRG3
Especie:
Human NRG3 (10718), Mouse Nrg3 (18183), Rat Nrg3 (498596), chicken NRG3 (428937), dog NRG3 (479263), Horse NRG3 (100065480), cow NRG3 (539977), domestic cat NRG3 (101082012), domestic guinea pig Nrg3 (100726543), naked mole-rat Nrg3 (101709491) ...Más
ID UniProtKB:
ID del gen:
- Human(10718) Summary: This gene is a member of the neuregulin gene family. This gene family encodes ligands for the transmembrane tyrosine kinase receptors ERBB3 and ERBB4 - members of the epidermal growth factor receptor family. Ligand binding activates intracellular signaling cascades and the induction of cellular responses including proliferation, migration, differentiation, and survival or apoptosis. This gene encodes neuregulin 3 (NRG3). NRG3 has been shown to activate the tyrosine phosphorylation of its cognate receptor, ERBB4, and is thought to influence neuroblast proliferation, migration and differentiation by signalling through ERBB4. NRG3 also promotes mammary differentiation during embryogenesis. Linkage studies have implicated this gene as a susceptibility locus for schizophrenia and schizoaffective disorder. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described but their biological validity has not been verified.[provided by RefSeq, Sep 2009]
- Mouse(18183) neuregulin 3
- Rat(498596) neuregulin 3
- chicken(428937) neuregulin 3
- dog(479263) neuregulin 3
- Horse(100065480) neuregulin 3
- cow(539977) neuregulin 3
- domestic cat(101082012) neuregulin 3
- domestic guinea pig(100726543) neuregulin 3
- naked mole-rat(101709491) neuregulin 3
- Domestic Rabbit(100337933) neuregulin 3
- sheep(101112537) neuregulin 3
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-Neuregulin-3 (NRG3) Antibody, clone 6V9X1, Rabbit Monoclonal, ,
Reactividad de especies
human, rat
Aplicación
western blot
esiRNA
Referencia del producto
Descripción
Especie