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Merck

NEFL

neurofilament, light polypeptide

Sinónimos:
CMT1F, CMT2E, NF-L, NF68, NFL
Especie:
ID UniProtKB:
ID del gen:
  • Human(4747) Summary: Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq, Oct 2008]
  • Mouse(18039) neurofilament, light polypeptide
  • Rat(83613) neurofilament, light polypeptide
  • chicken(419528) neurofilament, light polypeptide
  • cow(281348) neurofilament, light polypeptide
  • domestic cat(101081039) neurofilament, light polypeptide
  • dog(477378) neurofilament, light polypeptide
  • naked mole-rat(101704332) neurofilament, light polypeptide
  • domestic guinea pig(100731797) neurofilament, light polypeptide
  • sheep(101119539) neurofilament, light polypeptide

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Monoclonal Anti-Neurofilament 68 antibody produced in mouse, clone NR4, ascites fluid,
Reactividad de especies
chicken, human, pig, rat
Aplicación
immunohistochemistry
microarray

western blot
Anti-Neurofilament L Antibody, clone 1E13 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human
Aplicación
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot
Anti-Neurofilament-l antibody, Rabbit monoclonal, recombinant, expressed in HEK 293 cells, clone RM280, purified immunoglobulin,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
Monoclonal Anti-NEFL antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL4729, purified immunoglobulin,
Reactividad de especies
human, mouse, rat
Aplicación
immunofluorescence
immunohistochemistry

western blot
Anti-NEFL antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
immunofluorescence
immunohistochemistry

western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human NEFL,
Especie
human