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Merck

NANS

N-acetylneuraminic acid synthase

Sinónimos:
SAS
Especie:
ID UniProtKB:
ID del gen:
  • Human(54187) Summary: This gene encodes an enzyme that functions in the biosynthetic pathways of sialic acids. In vitro, the encoded protein uses N-acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN), respectively; however, it exhibits much higher activity toward the Neu5Ac phosphate product. In insect cells, expression of this gene results in Neu5Ac and KDN production. This gene is related to the E. coli sialic acid synthase gene neuB, and it can partially restore sialic acid synthase activity in an E. coli neuB-negative mutant. [provided by RefSeq, Jul 2008]
  • Mouse(94181) N-acetylneuraminic acid synthase (sialic acid synthase)
  • Rat(298071) N-acetylneuraminic acid synthase
  • sheep(101104048) N-acetylneuraminic acid synthase
  • domestic guinea pig(100716456) N-acetylneuraminic acid synthase
  • naked mole-rat(101721582) N-acetylneuraminic acid synthase
  • Domestic Rabbit(100356934) N-acetylneuraminic acid synthase
  • Zebrafish(322780) N-acetylneuraminic acid synthase
  • chicken(427283) N-acetylneuraminic acid synthase
  • domestic cat(101092303) N-acetylneuraminic acid synthase
  • cow(540602) N-acetylneuraminic acid synthase
  • Horse(100064126) N-acetylneuraminic acid synthase
  • dog(481624) N-acetylneuraminic acid synthase

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-NANS antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human, mouse, rat
Aplicación
immunofluorescence
immunohistochemistry

western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human NANS,
Especie
human
MISSION® esiRNA, targeting mouse Nans,
Especie
mouse