MCM2
minichromosome maintenance complex component 2
Sinónimos:
BM28, CCNL1, CDCL1, D3S3194, MITOTIN, cdc19
Especie:
Human MCM2 (4171), Mouse Mcm2 (17216), Rat Mcm2 (312538), domestic guinea pig Mcm2 (100722936), naked mole-rat Mcm2 (101710978), sheep MCM2 (101116097), Zebrafish mcm2 (192338), domestic cat MCM2 (101090176), dog MCM2 (484622), cow MCM2 (510120) ...Más
ID UniProtKB:
ID del gen:
- Human(4171) Summary: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq, Oct 2012]
- Mouse(17216) minichromosome maintenance deficient 2 mitotin (S. cerevisiae)
- Rat(312538) minichromosome maintenance complex component 2
- domestic guinea pig(100722936) minichromosome maintenance complex component 2
- naked mole-rat(101710978) minichromosome maintenance complex component 2
- sheep(101116097) minichromosome maintenance complex component 2
- Zebrafish(192338) MCM2 minichromosome maintenance deficient 2, mitotin (S. cerevisiae)
- domestic cat(101090176) minichromosome maintenance complex component 2
- dog(484622) minichromosome maintenance complex component 2
- cow(510120) minichromosome maintenance complex component 2
- chicken(416027) minichromosome maintenance complex component 2
- Thale Cress(841056) minichromosome maintenance protein 2
- fruit fly(40973) Minichromosome maintenance 2
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Rabbit anti-Phospho MCM2 (S108) Antibody, Affinity Purified, ,
Reactividad de especies
human, mouse
Aplicación
immunohistochemistry
western blot
western blot
Rabbit anti-MCM2 Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
Reactividad de especies
human, mouse
Aplicación
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-MCM2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-MCM2 antibody, Rabbit monoclonal, clone SP85, recombinant, expressed in proprietary host, affinity isolated antibody,
Reactividad de especies
bovine, dog, frog, human, mouse, rat
Aplicación
flow cytometry
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-MCM2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot