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Merck

MAPK1

mitogen-activated protein kinase 1

Sinónimos:
ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk
Especie:
ID UniProtKB:
ID del gen:
  • Human(5594) Summary: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(26413) mitogen-activated protein kinase 1
  • Rat(116590) mitogen activated protein kinase 1
  • Zebrafish(360144) mitogen-activated protein kinase 1
  • domestic cat(101087614) mitogen-activated protein kinase 1
  • cow(327672) mitogen-activated protein kinase 1
  • dog(477575) mitogen-activated protein kinase 1
  • chicken(373953) mitogen-activated protein kinase 1
  • sheep(101115485) mitogen-activated protein kinase 1
  • domestic guinea pig(100715180) mitogen-activated protein kinase 1
  • naked mole-rat(101706099) mitogen-activated protein kinase 1

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ELISA

Referencia del producto
Descripción
Especie
Phosphotyrosine MAPK1 / MAPK3 ELISA Kit, ,
Especie
human
Cell-Based ELISA for detecting phospho-ERK1 / 2 (pThr202 / pTyr204) in cultured cell lines, 96 assays,
Especie
mouse, rat, human
Cell-Based ELISA Sampler Kit for detecting phospho-ERK1/2 (pThr202/pTyr204), phospho-JNK (pThr183/pTyr185), and phospho-p38 MAPK (pThr180/pTyr182) in cultured cell lines, 192 assays,
Especie
rat, human, mouse

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-ERK2 antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot
Anti-MAPK1 antibody produced in chicken, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
human, mouse, rat
Aplicación
western blot
Anti-Phospho-ERK1-T202/Y204 + ERK2-T185/Y187 antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
immunoprecipitation (IP)

western blot
Anti-MAPK1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
Anti- ERK2 antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
Adenina, ≥99%,
Especie
human, rat, mouse
Adenina, BioReagent, suitable for cell culture,
Especie
human, rat, mouse
Adenina, BioReagent, suitable for plant cell culture, ≥99%,
Especie
human, rat, mouse

Proteins

Referencia del producto
Descripción
Especie
ERK2, active, GST tagged human, recombinant, expressed in E. coli, PRECISIO® Kinase, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human MAPK1,
Especie
human