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Merck

LIMS1

LIM and senescent cell antigen-like domains 1

Sinónimos:
PINCH, PINCH-1, PINCH1
Especie:
ID UniProtKB:
ID del gen:
  • Human(3987) Summary: The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]
  • Mouse(110829) LIM and senescent cell antigen-like domains 1
  • Rat(499443) LIM and senescent cell antigen-like domains 1
  • domestic guinea pig(100735007) LIM and senescent cell antigen-like domains 1
  • naked mole-rat(101696476) LIM and senescent cell antigen-like domains 1
  • sheep(101116555) LIM and senescent cell antigen-like domains 1
  • Zebrafish(554019) LIM and senescent cell antigen-like domains 1
  • chicken(414880) LIM and senescent cell antigen-like domains 1
  • dog(474540) LIM and senescent cell antigen-like domains 1
  • Horse(100060267) LIM and senescent cell antigen-like domains 1
  • cow(540281) LIM and senescent cell antigen-like domains 1
  • domestic cat(101094258) LIM and senescent cell antigen-like domains 1

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-LIMS1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
Anti-LIMS1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Monoclonal Anti-PINCH-1 antibody produced in mouse, clone PINCH-C58, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
bovine, canine, hamster, human, monkey, mouse, rat
Aplicación
ELISA
immunoprecipitation (IP)

western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Lims1,
Especie
mouse
MISSION® esiRNA, targeting human LIMS1,
Especie
human