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Merck

LEPR

leptin receptor

Sinónimos:
CD295, LEP-R, LEPRD, OB-R, OBR
Especie:
ID UniProtKB:
ID del gen:
  • Human(3953) Summary: The protein encoded by this gene belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated with obesity and pituitary dysfunction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. It is noteworthy that this gene and LEPROT gene (GeneID:54741) share the same promoter and the first 2 exons, however, encode distinct proteins (PMID:9207021).[provided by RefSeq, Nov 2010]
  • Mouse(16847) leptin receptor
  • Rat(24536) leptin receptor
  • sheep(443264) leptin receptor
  • domestic guinea pig(100725434) leptin receptor
  • naked mole-rat(101705981) leptin receptor
  • Zebrafish(567241) leptin receptor
  • dog(450207) leptin receptor
  • domestic cat(101085646) leptin receptor
  • cow(497205) leptin receptor
  • Horse(100033894) leptin receptor
  • chicken(374223) leptin receptor

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ELISA

Referencia del producto
Descripción
Especie
Mouse Lepr / Leptin Receptor ELISA Kit, ,
Especie
mouse

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-LEPR antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Anti-Leptin Receptor antibody produced in goat, affinity isolated antibody, lyophilized powder,
Reactividad de especies
mouse
Aplicación
flow cytometry
immunohistochemistry

western blot
Anti-Leptin Receptor Antibody, clone 6I0O4, Rabbit Monoclonal, ,
Reactividad de especies
human, rat
Aplicación
immunohistochemistry
western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human LEPR (2),
Especie
human
MISSION® esiRNA, targeting human LEPR,
Especie
human
MISSION® esiRNA, targeting mouse Lepr,
Especie
mouse