Saltar al contenido
Merck

LATS2

large tumor suppressor kinase 2

Sinónimos:
KPM
Especie:
ID UniProtKB:
ID del gen:
  • Human(26524) Summary: This gene encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression. [provided by RefSeq, Jul 2008]
  • Mouse(50523) large tumor suppressor 2
  • Rat(305922) large tumor suppressor 2
  • Zebrafish(567674) LATS, large tumor suppressor, homolog 2 (Drosophila)
  • cow(508208) large tumor suppressor kinase 2
  • Horse(100050150) LATS, large tumor suppressor, homolog 2 (Drosophila)
  • domestic cat(101093824) LATS, large tumor suppressor, homolog 2 (Drosophila)
  • dog(477343) LATS, large tumor suppressor, homolog 2 (Drosophila)
  • chicken(418949) LATS, large tumor suppressor, homolog 2 (Drosophila)
  • domestic guinea pig(100725954) large tumor suppressor kinase 2
  • naked mole-rat(101705060) large tumor suppressor kinase 2
  • sheep(101117941) LATS, large tumor suppressor, homolog 2 (Drosophila)
  • Domestic Rabbit(100356876) LATS, large tumor suppressor, homolog 2 (Drosophila)

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-LATS2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Anti-LATS2 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse
Aplicación
ELISA
immunofluorescence

immunohistochemistry
Anti-LATS2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunofluorescence
Anti-phospho-LATS1-T1079/LATS2-T1041 antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
western blot
Anti-phospho-LATS1/2 (pThr1079/1041) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse
Aplicación
immunohistochemistry

Proteins

Referencia del producto
Descripción
Especie
LATS2 (480-1088), GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Especie
human
PrEST Antigen LATS2, Prestige Antigens Powered by Atlas Antibodies, buffered aqueous solution,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human LATS2,
Especie
human