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Merck

KIT

v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

Sinónimos:
C-Kit, CD117, PBT, SCFR
Especie:
ID UniProtKB:
ID del gen:
  • Human(3815) Summary: This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(16590) kit oncogene
  • Rat(64030) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • chicken(378783) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • domestic cat(493766) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • cow(280832) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • Horse(100009704) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • dog(403811) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • Goat(100861386) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • sheep(780504) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • Domestic Rabbit(100327263) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • domestic guinea pig(100726397) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • naked mole-rat(101726400) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

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ELISA

Referencia del producto
Descripción
Especie
Human KIT / Mast/Stem Cell Growth Factor Receptor Kit ELISA Kit, ,
Especie
human
Phosphotyrosine KIT / Mast/stem Cell Growth Factor Receptor Kit ELISA Kit, ,
Especie
human

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-C-KIT antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
western blot
Anti-KIT antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Anti-KIT antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunofluorescence
Monoclonal Anti-KIT antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL1657, purified immunoglobulin, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
Monoclonal Anti-KIT antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL1667, purified immunoglobulin, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
Imatinib, ,
Especie
human
Sunitinib malate, ≥98% (HPLC),
Especie
human
Pazopanib, ,
Especie
human
Dasatinib, ≥98% (HPLC),
Especie
human
Dasatinib, ,
Especie
human

Proteins

Referencia del producto
Descripción
Especie
cKit active human, recombinant, expressed in baculovirus infected Sf9 cells, ≥32% (SDS-PAGE),
Especie
human
c-KIT (D820E), active, GST tagged human, PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Especie
human
c-KIT (N822K), active, GST tagged human, PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Especie
human
cKit active human, recombinant, expressed in baculovirus infected Sf9 cells, ≥22% (SDS-PAGE),
Especie
human
c-KIT (T670E), active, GST tagged human, PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Kit,
Especie
mouse
MISSION® esiRNA, targeting human KIT,
Especie
human