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Merck

KEAP1

kelch-like ECH-associated protein 1

Sinónimos:
INrf2, KLHL19
Especie:
ID UniProtKB:
ID del gen:
  • Human(9817) Summary: This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(50868) kelch-like ECH-associated protein 1
  • Rat(117519) Kelch-like ECH-associated protein 1
  • fruit fly(42062) CG3962 gene product from transcript CG3962-RC
  • cow(532791) kelch-like ECH-associated protein 1
  • dog(476713) kelch-like ECH-associated protein 1
  • domestic cat(101091260) kelch-like ECH-associated protein 1
  • sheep(101113845) kelch-like ECH-associated protein 1
  • domestic guinea pig(100713871) kelch-like ECH-associated protein 1
  • naked mole-rat(101718777) kelch-like ECH-associated protein 1

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-KEAP1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
Anti-KEAP1 Antibody, clone 3B9 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
affinity binding assay

immunocytochemistry

western blot
Anti- KEAP1 antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
Dimethyl fumarate, 97%,
Especie
human
Dimethyl Fumarate, Pharmaceutical Secondary Standard; Certified Reference Material,
Especie
human
Dimethyl fumarate, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland,
Especie
human
CDDO Methyl Ester, ≥98% (HPLC),
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human KEAP1,
Especie
human