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Merck

KDR

kinase insert domain receptor (a type III receptor tyrosine kinase)

Sinónimos:
CD309, FLK1, VEGFR, VEGFR2
Especie:
Human KDR (3791), Mouse Kdr (16542), Rat Kdr (25589), Goat KDR (100860836), sheep KDR (443087), Domestic Rabbit KDR (100008607), domestic guinea pig Kdr (100726761), naked mole-rat Kdr (101726029), Zebrafish kdr (554230), cow KDR (407170) ...Más
ID UniProtKB:
P35968, A2RRS0, B5A925, C5IFA0, O60723, Q14178
ID del gen:
  • Human(3791) Summary: Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq, May 2009]
  • Mouse(16542) kinase insert domain protein receptor
  • Rat(25589) kinase insert domain receptor
  • Goat(100860836) kinase insert domain receptor (a type III receptor tyrosine kinase)
  • sheep(443087) vascular endothelial growth factor receptor-2
  • Domestic Rabbit(100008607) kinase insert domain receptor (a type III receptor tyrosine kinase)
  • domestic guinea pig(100726761) kinase insert domain receptor (a type III receptor tyrosine kinase)
  • naked mole-rat(101726029) kinase insert domain receptor (a type III receptor tyrosine kinase)
  • Zebrafish(554230) kinase insert domain receptor (a type III receptor tyrosine kinase)
  • cow(407170) kinase insert domain receptor (a type III receptor tyrosine kinase)
  • Horse(100033959) kinase insert domain receptor (a type III receptor tyrosine kinase)
  • domestic cat(101090260) kinase insert domain receptor (a type III receptor tyrosine kinase)
  • dog(482154) kinase insert domain receptor (a type III receptor tyrosine kinase)
  • chicken(395323) kinase insert domain receptor (a type III receptor tyrosine kinase)
  • Thale Cress(839585) basic helix-loop-helix protein KIDARI

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ELISA

Referencia del producto
Descripción
Especie
RAB0328
Human VEGF R2 ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Especie
human
RAB0858
Mouse Kdr / Vascular Endothelial Growth Factor Receptor 2 ELISA Kit, ,
Especie
mouse

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
SAB4501645
Anti-VEGFR2 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse
Aplicación
ELISA
immunohistochemistry
western blot
V3003
Monoclonal Anti-Vascular Endothelial Growth Factor Receptor-2 (KDR) antibody produced in mouse, clone 260.4, KDR-2, ascites fluid,
Reactividad de especies
human
Aplicación
ELISA
immunohistochemistry
western blot
ZRB1209
Anti-VEGFR-2 Antibody, clone 3E21 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human
Aplicación
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
GW21181
Anti-VEGFR-2 antibody produced in chicken, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot
V9134
Monoclonal Anti-Vascular Endothelial Growth Factor Receptor-2 antibody produced in mouse, clone KDR-1, ascites fluid,
Reactividad de especies
human
Aplicación
ELISA
immunohistochemistry

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
PZ0193
Axitinib, ≥98% (HPLC),
Especie
human
C8863
7-Cyclopentyl-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3‑d]pyrimidin-4-ylamine, ≥98% (HPLC),
Especie
human
S8442
SU 5416, ≥98% (HPLC),
Especie
human, mouse
PZ0012
Sunitinib malate, ≥98% (HPLC),
Especie
human
CDS023580
Pazopanib, ,
Especie
human

Proteins

Referencia del producto
Descripción
Especie
V6758
VEGF Receptor-2 (Flk-1, KDR)/Fc Chimera human, >90% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder,
Especie
human
K2643
KDR (789-end), active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
EHU155611
MISSION® esiRNA, targeting human KDR,
Especie
human
EMU052221
MISSION® esiRNA, targeting mouse Kdr,
Especie
mouse