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Merck

KCNH2

potassium voltage-gated channel, subfamily H (eag-related), member 2

Sinónimos:
ERG1, HERG, HERG1, Kv11.1, LQT2, SQT1
Especie:
ID UniProtKB:
ID del gen:
  • Human(3757) Summary: This gene encodes a voltage-activated potassium channel belonging to the eag family. It shares sequence similarity with the Drosophila ether-a-go-go (eag) gene. Mutations in this gene can cause long QT syndrome type 2 (LQT2). Transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008]
  • Mouse(16511) potassium voltage-gated channel, subfamily H (eag-related), member 2
  • Rat(117018) potassium voltage-gated channel, subfamily H (eag-related), member 2
  • Zebrafish(405763) potassium voltage-gated channel, subfamily H (eag-related), member 2
  • domestic cat(101081621) potassium voltage-gated channel, subfamily H (eag-related), member 2
  • cow(539971) potassium voltage-gated channel, subfamily H (eag-related), member 2
  • Horse(100064000) potassium voltage-gated channel, subfamily H (eag-related), member 2
  • dog(403761) potassium voltage-gated channel, subfamily H (eag-related), member 2
  • domestic guinea pig(100135563) potassium voltage-gated channel, subfamily H (eag-related), member 2
  • naked mole-rat(101711977) potassium voltage-gated channel, subfamily H (eag-related), member 2
  • Domestic Rabbit(100009242) potassium voltage-gated channel, subfamily H (eag-related), member 2

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Small Molecule - Antagonist

Referencia del producto
Descripción
Especie
Sotalol hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Sotalol hydrochloride, British Pharmacopoeia (BP) Reference Standard,
Especie
human
(±)-Sotalol hydrochloride, ≥98% (TLC), powder,
Especie
human
Glyburide, meets USP testing specifications,
Especie
rat, human
Glybenclamide, ≥99% (HPLC),
Especie
rat, human

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-Potassium Channel KV11.1 (HERG) Extracellular-FITC antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Reactividad de especies
human
Aplicación
flow cytometry
immunocytochemistry
Anti-Potassium Channel Kv11.1 Extracellular antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Reactividad de especies
human
Aplicación
flow cytometry
immunocytochemistry

western blot
Anti-Potassium Channel hKv11.1 antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Reactividad de especies
human
Aplicación
western blot

Small Molecule - Blocker

Referencia del producto
Descripción
Especie
Dofetilide, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Ibutilide hemifumarate salt, ≥98% (HPLC),
Especie
human
Ibutilide fumarate, United States Pharmacopeia (USP) Reference Standard, monograph mol wt. 885.23 ([(C20H36N2O3S)2 . C4H4O4]),
Especie
human
Sotalol hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Sotalol hydrochloride, British Pharmacopoeia (BP) Reference Standard,
Especie
human

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
Loratadine, ≥98% (HPLC), powder,
Especie
rat, human
Terfenadine, ,
Especie
mouse, rat, human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human KCNH2,
Especie
human