Saltar al contenido
MilliporeSigma

ITGAV

integrin, alpha V

Sinónimos:
CD51, MSK8, VNRA, VTNR
Especie:
ID UniProtKB:
ID del gen:
  • Human(3685) Summary: This gene encodes a protein that is a member of the integrin superfamily. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein undergoes post-translational cleavage to yield disulfide-linked heavy and light chains that combine with multiple integrin beta chains to form different integrins. This protein has been shown to heterodimerize with beta 1, beta 3, beta 5, beta 6, and beta 8; the heterodimer of alpha v and beta 3 is the Vitronectin receptor. This protein interacts with several extracellular matrix proteins to mediate cell adhesion and may play a role in cell migration. It is proposed that this protein may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, May 2013]
  • Mouse(16410) integrin alpha V
  • Rat(296456) integrin, alpha V
  • sheep(443143) integrin, alpha V
  • Domestic Rabbit(100008956) integrin, alpha V
  • domestic guinea pig(100728575) integrin, alpha V
  • naked mole-rat(101717672) integrin, alpha V
  • Zebrafish(100151255) integrin, alpha V
  • cow(281875) integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)
  • Horse(100068706) integrin, alpha V
  • domestic cat(101085820) integrin, alpha V
  • dog(488437) integrin, alpha V
  • chicken(396420) integrin, alpha V

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Small Molecule - Antagonist

Product Number
Descripción
Especie
Gly-Arg-Gly-Asp-Ser-Pro-Lys, ≥97% (HPLC),
Especie
human

Antibodies

Product Number
Descripción
Reactividad de especies
Aplicación
Anti-Integrin αVβ8 Antibody, clone EM13309 , ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human
Aplicación
flow cytometry
immunocytochemistry

immunohistochemistry

western blot
Anti-Integrin αVβ3 Antibody, clone EM22703 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human
Aplicación
flow cytometry
immunocytochemistry

immunofluorescence

immunohistochemistry
Anti-Integrin αVβ5 Antibody, clone EM09902 , ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human
Aplicación
flow cytometry
immunocytochemistry

immunohistochemistry

western blot
Anti-Integrin pan-αV Antibody, clone EM01309 , ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human
Aplicación
flow cytometry
immunocytochemistry

immunohistochemistry

western blot
Anti-ITGAV antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry

esiRNA

Product Number
Descripción
Especie
MISSION® esiRNA, targeting mouse Itgav,
Especie
mouse
MISSION® esiRNA, targeting human ITGAV,
Especie
human