Saltar al contenido
Merck

HHIP

hedgehog interacting protein

Sinónimos:
HIP
Especie:
ID UniProtKB:
ID del gen:
  • Human(64399) Summary: This gene encodes a member of the hedgehog-interacting protein (HHIP) family. The hedgehog (HH) proteins are evolutionarily conserved protein, which are important morphogens for a wide range of developmental processes, including anteroposterior patterns of limbs and regulation of left-right asymmetry in embryonic development. Multiple cell-surface receptors are responsible for transducing and/or regulating HH signals. The HHIP encoded by this gene is a highly conserved, vertebrate-specific inhibitor of HH signaling. It interacts with all three HH family members, SHH, IHH and DHH. Two single nucleotide polymorphisms (SNPs) near this gene are significantly associated with risk of chronic obstructive pulmonary disease (COPD). A single nucleotide polymorphism in this gene is also strongly associated with human height.[provided by RefSeq, Feb 2011]
  • Mouse(15245) Hedgehog-interacting protein
  • Rat(291936) Hedgehog-interacting protein
  • sheep(101111396) hedgehog interacting protein
  • Domestic Rabbit(100344588) hedgehog interacting protein
  • domestic guinea pig(100728644) hedgehog interacting protein
  • naked mole-rat(101724427) hedgehog interacting protein
  • Zebrafish(326102) hedgehog interacting protein
  • domestic cat(101087058) hedgehog interacting protein
  • cow(540830) hedgehog interacting protein
  • Horse(100062868) hedgehog interacting protein
  • dog(475452) hedgehog interacting protein
  • chicken(422460) hedgehog interacting protein

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-HHIP antibody produced in rabbit, ,
Reactividad de especies
chicken, human, mouse
Aplicación
immunocytochemistry
immunofluorescence

immunohistochemistry

western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Hhip,
Especie
mouse
MISSION® esiRNA, targeting human HHIP,
Especie
human