HDAC8
histone deacetylase 8
Sinónimos:
CDLS5, HD8, HDACL1, MRXS6, RPD3, WTS
Especie:
Human HDAC8 (55869), Mouse Hdac8 (70315), Rat Hdac8 (363481), Zebrafish hdac8 (406740), cow HDAC8 (540666), domestic cat HDAC8 (101096383), dog HDAC8 (480957), chicken HDAC8 (422182), domestic guinea pig Hdac8 (100721893), naked mole-rat Hdac8 (101697998)
ID UniProtKB:
ID del gen:
- Human(55869) Summary: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
- Mouse(70315) histone deacetylase 8
- Rat(363481) histone deacetylase 8
- Zebrafish(406740) histone deacetylase 8
- cow(540666) histone deacetylase 8
- domestic cat(101096383) histone deacetylase 8
- dog(480957) histone deacetylase 8
- chicken(422182) histone deacetylase 8
- domestic guinea pig(100721893) histone deacetylase 8
- naked mole-rat(101697998) histone deacetylase 8
- sheep(101110121) histone deacetylase 8
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Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Monoclonal Anti-Histone Deacetylase 8 (HDAC8) antibody produced in mouse, 2.0-2.5 mg/mL, clone HDAC8-48, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
microarray
western blot
microarray
western blot
Anti-HDAC8 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-phospho-HDAC8 (pSer39) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
immunohistochemistry
[KO Validated]Anti-HDAC8 Antibody, clone 1O2Y5, Rabbit Monoclonal, ,
Reactividad de especies
human, rat
Aplicación
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-HDAC8 antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Small Molecule - Inhibitor
Kits
Referencia del producto
Descripción
Especie
Histone Deacetylase 8 (HDAC8) Inhibitor Screening Kit, 100 assays in 96 well plates,
Especie
human, mouse
Proteins
Referencia del producto
Descripción
Especie
HDAC-8 human, recombinant, expressed in baculovirus infected insect cells, ≥80% (SDS-PAGE),
Especie
human