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Merck

HCN4

hyperpolarization activated cyclic nucleotide-gated potassium channel 4

Sinónimos:
SSS2
Especie:
ID UniProtKB:
ID del gen:
  • Human(10021) Summary: This gene encodes a member of the hyperpolarization-activated cyclic nucleotide-gated potassium channels. The encoded protein shows slow kinetics of activation and inactivation, and is necessary for the cardiac pacemaking process. This channel may also mediate responses to sour stimuli. Mutations in this gene have been linked to sick sinus syndrome 2, also known as atrial fibrillation with bradyarrhythmia or familial sinus bradycardia. Two pseudogenes have been identified on chromosome 15. [provided by RefSeq, Oct 2008]
  • Mouse(330953) hyperpolarization-activated, cyclic nucleotide-gated K+ 4
  • Rat(59266) hyperpolarization activated cyclic nucleotide-gated potassium channel 4
  • domestic guinea pig(100717049) hyperpolarization activated cyclic nucleotide-gated potassium channel 4
  • naked mole-rat(101715130) hyperpolarization activated cyclic nucleotide-gated potassium channel 4
  • sheep(101117337) hyperpolarization activated cyclic nucleotide-gated potassium channel 4
  • Domestic Rabbit(100009452) hyperpolarization activated cyclic nucleotide-gated potassium channel 4
  • Zebrafish(557843) hyperpolarization activated cyclic nucleotide-gated potassium channel 4
  • cow(785689) hyperpolarization activated cyclic nucleotide-gated potassium channel 4
  • domestic cat(101090363) hyperpolarization activated cyclic nucleotide-gated potassium channel 4
  • dog(448794) hyperpolarization activated cyclic nucleotide-gated potassium channel 4
  • chicken(427478) hyperpolarization activated cyclic nucleotide-gated potassium channel 4

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Monoclonal Anti-HCN4 antibody produced in mouse, clone S114-10, 1 mg/mL, purified immunoglobulin,
Reactividad de especies
human, mouse, rat
Aplicación
immunocytochemistry
immunohistochemistry

western blot
Anti-HCN4, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunohistochemistry
Anti-HCN4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry

Small Molecule - Blocker

Referencia del producto
Descripción
Especie
Ivabradine hydrochloride, ≥98% (HPLC),
Especie
human
Dronedarone hydrochloride, ≥98% (HPLC),
Especie
human
Dronedarone hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Especie
human
Dronedarone hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Especie
human