GRM2
glutamate receptor, metabotropic 2
Sinónimos:
GLUR2, GPRC1B, MGLUR2, mGlu2
Especie:
Human GRM2 (2912), Mouse Grm2 (108068), Rat Grm2 (24415), chicken GRM2 (427575), dog GRM2 (484751), domestic cat GRM2 (101098611), cow GRM2 (519904), Horse GRM2 (100052178), sheep GRM2 (101116870), domestic guinea pig Grm2 (100720736)
ID UniProtKB:
ID del gen:
- Human(2912) Summary: L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(108068) glutamate receptor, metabotropic 2
- Rat(24415) glutamate receptor, metabotropic 2
- chicken(427575) glutamate receptor, metabotropic 2
- dog(484751) glutamate receptor, metabotropic 2
- domestic cat(101098611) glutamate receptor, metabotropic 2
- cow(519904) glutamate receptor, metabotropic 2
- Horse(100052178) glutamate receptor, metabotropic 2
- sheep(101116870) glutamate receptor, metabotropic 2
- domestic guinea pig(100720736) glutamate receptor, metabotropic 2
- naked mole-rat(101722804) glutamate receptor, metabotropic 2
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Small Molecule - Agonist
Small Molecule - Antagonist
Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-GRM2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Anti-MGLUR2 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-GRM2 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
immunofluorescence
immunohistochemistry
immunofluorescence
immunohistochemistry
Anti-mGluR2 antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot
western blot
Small Molecule - Inhibitor
Referencia del producto
Descripción
Especie
L-(+)-2-Amino-4-phosphonobutyric acid, optical purity optical purity: ≥95% (HPLC, Marfey′s reagent),
Especie
rat, human
Small Molecule - Ligand
Referencia del producto
Descripción
Especie
Small Molecule - Mixed Agonist/Antagonist
Referencia del producto
Descripción
Especie
L-(+)-2-Amino-4-phosphonobutyric acid, optical purity optical purity: ≥95% (HPLC, Marfey′s reagent),
Especie
rat, human
L-Glutamic acid, from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-100.5%,
Especie
rat, human
esiRNA
Referencia del producto
Descripción
Especie