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Merck

GRIN2A

glutamate receptor, ionotropic, N-methyl D-aspartate 2A

Sinónimos:
EPND, GluN2A, NMDAR2A, NR2A
Especie:
Human GRIN2A (2903), Mouse Grin2a (14811), Rat Grin2a (24409), chicken GRIN2A (427678), dog GRIN2A (490012), domestic cat GRIN2A (101086110), sheep GRIN2A (101106989), domestic guinea pig Grin2a (100727265)
ID UniProtKB:
Q12879, O00669, Q17RZ6
ID del gen:
  • Human(2903) Summary: N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate-gated ion channels. These receptors have been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C) and NMDAR2D (GRIN2D). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
  • Mouse(14811) glutamate receptor, ionotropic, NMDA2A (epsilon 1)
  • Rat(24409) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • chicken(427678) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • dog(490012) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • domestic cat(101086110) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • sheep(101106989) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • domestic guinea pig(100727265) glutamate receptor, ionotropic, N-methyl D-aspartate 2A

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Small Molecule - Agonist

Referencia del producto
Descripción
Especie
239488
1,4-Bis(3-aminopropyl)piperazine, ≥99%,
Especie
rat
1181007
Dextromethorphan hydrobromide, United States Pharmacopeia (USP) Reference Standard,
Especie
human
PHR1018
Dextromethorphan HBr, certified reference material, pharmaceutical secondary standard,
Especie
human
D9684
Dextromethorphan hydrobromide, meets USP testing specifications,
Especie
human
R1276
Reversin 121, ≥97% (HPLC), powder,
Especie
mouse, rat, human

Small Molecule - Allosteric Modulator

Referencia del producto
Descripción
Especie
K0250
Ácido kaínico monohydrate, ≥99% (TLC),
Especie
human, mouse, rat
A6981
Acamprosate calcium, ≥98% (HPLC), powder,
Especie
human
1000554
Acamprosate calcium, United States Pharmacopeia (USP) Reference Standard, monograph mol wt. 400.48 (C10H20CaN2O8S2),
Especie
human
BP1172
Acamprosate calcium, British Pharmacopoeia (BP) Reference Standard,
Especie
human
A78403
4-Aminopyridine, 98%,
Especie
rat, human, mouse

Small Molecule - Antagonist

Referencia del producto
Descripción
Especie
G7126
Glicina, ReagentPlus®, ≥99% (HPLC),
Especie
rat
G8898
Glicina, suitable for electrophoresis, ≥99%,
Especie
rat
50046
Glicina, BioUltra, for molecular biology, ≥99.0% (NT),
Especie
rat
G8790
Glicina, from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, ≥98.5%,
Especie
rat
G5417
Glicina, ,
Especie
rat

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
SAB5200888
Monoclonal Anti-Glun2A/Nr2A antibody produced in mouse, clone S327-95, purified immunoglobulin,
Reactividad de especies
human, mouse, rat
Aplicación
immunocytochemistry
immunohistochemistry
western blot
SAB5200988
Monoclonal Anti-Glun2A/Nr2A - Apc antibody produced in mouse, clone S327A-38, purified immunoglobulin,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot
SAB5200978
Monoclonal Anti-Glun2A/Nr2A antibody produced in mouse, clone S327A-38, purified immunoglobulin,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot
SAB5200898
Monoclonal Anti-Glun2A/Nr2A - Apc antibody produced in mouse, clone S327-95, purified immunoglobulin,
Reactividad de especies
human, mouse, rat
Aplicación
immunocytochemistry
immunohistochemistry
western blot
SAB5200904
Monoclonal Anti-Glun2A/Nr2A - Rpe antibody produced in mouse, clone S327-95, purified immunoglobulin,
Reactividad de especies
human, mouse, rat
Aplicación
immunocytochemistry
immunohistochemistry
western blot

Small Molecule - Blocker

Referencia del producto
Descripción
Especie
D8816
N-(3,3-Diphenylpropyl)glycinamide, >98% (HPLC), solid,
Especie
human
A7127
Agmatine sulfate salt, ≥97%, powder,
Especie
human
K3375
Kynurenic acid, ≥98%,
Especie
rat, human
A78403
4-Aminopyridine, 98%,
Especie
rat, human, mouse
275875
4-Aminopyridine, ≥99%,
Especie
rat, human, mouse

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
I5109
Indole-2-carboxylic acid, 98%,
Especie
rat, human
D207756
1,3-Diphenylguanidine, 97%,
Especie
rat, mouse, human
Q2128
Quisqualic acid, powder,
Especie
rat
N5501
Nω-Nitro-L-arginine, ≥98% (TLC),
Especie
rat, mouse, human
P0547
Pentamidine isethionate salt, powder,
Especie
human

Small Molecule - Mixed Agonist/Antagonist

Referencia del producto
Descripción
Especie
308110
N,N′-Dimethyl-1,3-propanediamine, 97%,
Especie
rat
549983
N,N,N′,N′-Tetramethyl-1,3-propanediamine, ≥99%,
Especie
rat
D18609
1,3-Diamino-2-propanol, 95%,
Especie
rat
127027
N-Methyl-1,3-diaminopropane, 98%,
Especie
rat
226920
2,2-Dimethyl-1,3-propanediamine, 99%,
Especie
rat

esiRNA

Referencia del producto
Descripción
Especie
EHU040271
MISSION® esiRNA, targeting human GRIN2A,
Especie
human
EMU051581
MISSION® esiRNA, targeting mouse Grin2a,
Especie
mouse