GRIA4
glutamate receptor, ionotropic, AMPA 4
Sinónimos:
GLUR4, GLUR4C, GLURD, GluA4
Especie:
Human GRIA4 (2893), Mouse Gria4 (14802), Rat Gria4 (29629), chicken GRIA4 (396137), dog GRIA4 (489427), Horse GRIA4 (100061561), cow GRIA4 (529904), domestic cat GRIA4 (101087003), domestic guinea pig Gria4 (100728256), naked mole-rat Gria4 (101698538)
ID UniProtKB:
ID del gen:
- Human(2893) Summary: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties. Some haplotypes of this gene show a positive association with schizophrenia. [provided by RefSeq, Jul 2008]
- Mouse(14802) glutamate receptor, ionotropic, AMPA4 (alpha 4)
- Rat(29629) glutamate receptor, ionotropic, AMPA 4
- chicken(396137) glutamate receptor, ionotropic, AMPA 4
- dog(489427) glutamate receptor, ionotropic, AMPA 4
- Horse(100061561) glutamate receptor, ionotropic, AMPA 4
- cow(529904) glutamate receptor, ionotrophic, AMPA 4
- domestic cat(101087003) glutamate receptor, ionotropic, AMPA 4
- domestic guinea pig(100728256) glutamate receptor, ionotropic, AMPA 4
- naked mole-rat(101698538) glutamate receptor, ionotropic, AMPA 4
- sheep(443274) glutamate receptor, ionotropic, AMPA 4
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Small Molecule - Agonist
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2,6-Difluoro-4-[2-(phenylsulfonylamino)ethylthio]phenoxyacetamide, ≥98% (HPLC), solid,
Especie
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Small Molecule - Allosteric Modulator
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Small Molecule - Antagonist
Antibodies
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Reactividad de especies
Aplicación
Anti-Gria4 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
Anti-GLUR4 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
western blot
western blot
Anti-GluR4/GluA4/GRIA4 Antibody, clone 4M5D0, Rabbit Monoclonal, ,
Reactividad de especies
mouse, rat
Aplicación
western blot
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Small Molecule - Mixed Agonist/Antagonist
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Especie
rat, human