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GPX1

glutathione peroxidase 1

Sinónimos:
GPXD, GSHPX1
Especie:
ID UniProtKB:
ID del gen:
  • Human(2876) Summary: This gene encodes a member of the glutathione peroxidase family. Glutathione peroxidase functions in the detoxification of hydrogen peroxide, and is one of the most important antioxidant enzymes in humans. This protein is one of only a few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by UGA, that normally functions as a translation termination codon. In addition, this protein is characterized in a polyalanine sequence polymorphism in the N-terminal region, which includes three alleles with five, six or seven alanine (ALA) repeats in this sequence. The allele with five ALA repeats is significantly associated with breast cancer risk. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(14775) glutathione peroxidase 1
  • Rat(24404) glutathione peroxidase 1
  • Thale Cress(817046) phospholipid hydroperoxide glutathione peroxidase 1
  • chicken(100857115) glutathione peroxidase 1
  • domestic cat(101083751) glutathione peroxidase 1
  • cow(281209) glutathione peroxidase 1
  • Horse(100053396) glutathione peroxidase 1
  • dog(442961) glutathione peroxidase 1
  • sheep(100820742) glutathione peroxidase 1
  • Domestic Rabbit(100009258) glutathione peroxidase 1
  • domestic guinea pig(100729115) glutathione peroxidase 1
  • naked mole-rat(101710466) glutathione peroxidase 1

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-GPX1 Antibody, clone 1J19 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
canine, feline, human, monkey, porcine
Aplicación
immunocytochemistry
immunohistochemistry

western blot
ANTI-FLAG® M2-Peroxidasa (HRP) monoclonal antibody produced in mouse, clone M2, purified immunoglobulin, buffered aqueous glycerol solution,
Reactividad de especies
all
Aplicación
ELISA
Anti-GPX1 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
alligator, human, mouse, rat
Aplicación
immunofluorescence
immunohistochemistry

western blot
Anti-GPX1 antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot

Proteins

Referencia del producto
Descripción
Especie
GPX1 human, recombinant, expressed in E. coli, His tagged, >90% (SDS-PAGE),
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human GPX1,
Especie
human