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Merck

GABRG3

gamma-aminobutyric acid (GABA) A receptor, gamma 3

Sinónimos:
Especie:
ID UniProtKB:
ID del gen:
  • Human(2567) Summary: This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. The protein encoded by this gene is a gamma subunit, which contains the benzodiazepine binding site. Two transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Aug 2012]
  • Mouse(14407) gamma-aminobutyric acid (GABA) A receptor, subunit gamma 3
  • Rat(79211) gamma-aminobutyric acid (GABA) A receptor, gamma 3
  • domestic guinea pig(100729690) gamma-aminobutyric acid (GABA) A receptor, gamma 3
  • naked mole-rat(101712623) gamma-aminobutyric acid (GABA) A receptor, gamma 3
  • sheep(101108521) gamma-aminobutyric acid (GABA) A receptor, gamma 3
  • Zebrafish(567057) gamma-aminobutyric acid (GABA) A receptor, gamma 3
  • cow(613670) gamma-aminobutyric acid (GABA) A receptor, gamma 3
  • domestic cat(101094182) gamma-aminobutyric acid (GABA) A receptor, gamma 3
  • dog(488685) gamma-aminobutyric acid (GABA) A receptor, gamma 3
  • chicken(770097) gamma-aminobutyric acid (GABA) A receptor, gamma 3

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Small Molecule - Allosteric Modulator

Referencia del producto
Descripción
Especie
Propofol, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Flunitrazepam, British Pharmacopoeia (BP) Reference Standard,
Especie
human
Propofol, European Pharmacopoeia (EP) Reference Standard,
Especie
human
Propofol, Pharmaceutical Secondary Standard; Certified Reference Material,
Especie
human
Alprazolam, European Pharmacopoeia (EP) Reference Standard,
Especie
human

Small Molecule - Antagonist

Referencia del producto
Descripción
Especie
Flumazenil, United States Pharmacopeia (USP) Reference Standard,
Especie
human
2,6-Diisopropylphenol, 97%,
Especie
human
Flumazenil, >99% (HPLC), solid,
Especie
rat, human
Acamprosate calcium, ≥98% (HPLC), powder,
Especie
human
Acamprosate calcium, United States Pharmacopeia (USP) Reference Standard, monograph mol wt. 400.48 (C10H20CaN2O8S2),
Especie
human

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-GABRG3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Anti-GABRG3 antibody produced in rabbit, IgG fraction of antiserum,
Reactividad de especies
human
Aplicación
western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human GABRG3,
Especie
human