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Merck

FGD1

FYVE, RhoGEF and PH domain containing 1

Sinónimos:
AAS, FGDY, MRXS16, ZFYVE3
Especie:
ID UniProtKB:
ID del gen:
  • Human(2245) Summary: This gene encodes a protein that contains Dbl (DH) and pleckstrin (PH) homology domains and is similar to the Rho family of small GTP-binding proteins. The encoded protein specifically binds to the Rho family GTPase Cdc42Hs and can stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. Defects in this gene are the cause of faciogenital dysplasia and X-linked mental retardation, syndromatic 16.[provided by RefSeq, Mar 2011]
  • Mouse(14163) FYVE, RhoGEF and PH domain containing 1
  • Rat(363460) FYVE, RhoGEF and PH domain containing 1
  • Zebrafish(560305) FYVE, RhoGEF and PH domain containing 1
  • dog(491901) FYVE, RhoGEF and PH domain containing 1
  • domestic cat(101094403) FYVE, RhoGEF and PH domain containing 1
  • cow(100124501) FYVE, RhoGEF and PH domain containing 1
  • sheep(101117050) FYVE, RhoGEF and PH domain containing 1
  • domestic guinea pig(100718541) FYVE, RhoGEF and PH domain containing 1
  • naked mole-rat(101720101) FYVE, RhoGEF and PH domain containing 1

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-Fgd1 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Anti-FGD1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Fgd1,
Especie
mouse
MISSION® esiRNA, targeting human FGD1,
Especie
human