DDR2
discoidin domain receptor tyrosine kinase 2
Sinónimos:
MIG20a, NTRKR3, TKT, TYRO10
Especie:
Human DDR2 (4921), Mouse Ddr2 (18214), Rat Ddr2 (685781), Zebrafish ddr2 (559428), dog DDR2 (478987), chicken DDR2 (396404), Horse DDR2 (100058300), cow DDR2 (533523), domestic cat DDR2 (101085267), sheep DDR2 (101109754) ...Más
ID UniProtKB:
ID del gen:
- Human(4921) Summary: Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation, and metabolism. In several cases the biochemical mechanism by which RTKs transduce signals across the membrane has been shown to be ligand induced receptor oligomerization and subsequent intracellular phosphorylation. This autophosphorylation leads to phosphorylation of cytosolic targets as well as association with other molecules, which are involved in pleiotropic effects of signal transduction. RTKs have a tripartite structure with extracellular, transmembrane, and cytoplasmic regions. This gene encodes a member of a novel subclass of RTKs and contains a distinct extracellular region encompassing a factor VIII-like domain. Alternative splicing in the 5' UTR results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
- Mouse(18214) discoidin domain receptor family, member 2
- Rat(685781) discoidin domain receptor tyrosine kinase 2
- Zebrafish(559428) discoidin domain receptor family, member 2
- dog(478987) discoidin domain receptor tyrosine kinase 2
- chicken(396404) discoidin domain receptor tyrosine kinase 2
- Horse(100058300) discoidin domain receptor tyrosine kinase 2
- cow(533523) discoidin domain receptor tyrosine kinase 2
- domestic cat(101085267) discoidin domain receptor tyrosine kinase 2
- sheep(101109754) discoidin domain receptor tyrosine kinase 2
- naked mole-rat(101712349) discoidin domain receptor tyrosine kinase 2
- domestic guinea pig(100729537) discoidin domain receptor tyrosine kinase 2
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Anti-DDR2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
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human
Aplicación
immunofluorescence
Anti-DDR2 Antibody, clone 1M8U7, Rabbit Monoclonal, ,
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human, rat
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western blot
esiRNA
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