DCC
deleted in colorectal carcinoma
Sinónimos:
CRC18, CRCR1, IGDCC1, MRMV1
Especie:
Human DCC (1630), Mouse Dcc (13176), Rat Dcc (25311), Zebrafish dcc (569360), dog DCC (483976), cow DCC (537176), Horse DCC (100054013), domestic cat DCC (101098832), domestic guinea pig Dcc (100712666), naked mole-rat Dcc (101705571)
ID UniProtKB:
ID del gen:
- Human(1630) Summary: This gene encodes a netrin 1 receptor. The transmembrane protein is a member of the immunoglobulin superfamily of cell adhesion molecules, and mediates axon guidance of neuronal growth cones towards sources of netrin 1 ligand. The cytoplasmic tail interacts with the tyrosine kinases Src and focal adhesion kinase (FAK, also known as PTK2) to mediate axon attraction. The protein partially localizes to lipid rafts, and induces apoptosis in the absence of ligand. The protein functions as a tumor suppressor, and is frequently mutated or downregulated in colorectal cancer and esophageal carcinoma. [provided by RefSeq, Oct 2009]
- Mouse(13176) deleted in colorectal carcinoma
- Rat(25311) deleted in colorectal carcinoma
- Zebrafish(569360) deleted in colorectal carcinoma
- dog(483976) deleted in colorectal carcinoma
- cow(537176) deleted in colorectal carcinoma
- Horse(100054013) deleted in colorectal carcinoma
- domestic cat(101098832) deleted in colorectal carcinoma
- domestic guinea pig(100712666) deleted in colorectal carcinoma
- naked mole-rat(101705571) deleted in colorectal carcinoma
- sheep(101118654) deleted in colorectal carcinoma
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Antibodies
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Reactividad de especies
Aplicación
Anti-DCC antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
immunofluorescence
immunofluorescence
Anti-DCC antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Anti-DCC antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunofluorescence
esiRNA
Referencia del producto
Descripción
Especie