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Merck

CTNNB1

catenin (cadherin-associated protein), beta 1, 88kDa

Sinónimos:
CTNNB, MRD19, armadillo
Especie:
ID UniProtKB:
ID del gen:
  • Human(1499) Summary: The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Oct 2009]
  • Mouse(12387) catenin (cadherin associated protein), beta 1
  • Rat(84353) catenin (cadherin associated protein), beta 1
  • naked mole-rat(101720578) catenin (cadherin-associated protein), beta 1, 88kDa
  • domestic guinea pig(100732604) catenin (cadherin-associated protein), beta 1, 88kDa
  • sheep(100294600) catenin (cadherin-associated protein), beta 1, 88kDa
  • Domestic Rabbit(100125985) catenin (cadherin-associated protein), beta 1, 88kDa
  • Zebrafish(30265) catenin (cadherin-associated protein), beta 1
  • chicken(395964) catenin (cadherin-associated protein), beta 1, 88kDa
  • cow(539003) catenin (cadherin-associated protein), beta 1, 88kDa
  • Horse(100055241) catenin (cadherin-associated protein), beta 1, 88kDa
  • domestic cat(101097342) catenin (cadherin-associated protein), beta 1, 88kDa
  • dog(477032) catenin (cadherin-associated protein), beta 1, 88kDa

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Monoclonal Anti-β-Catenin antibody produced in mouse, clone 15B8, ascites fluid,
Reactividad de especies
bovine, canine, chicken, human
Aplicación
immunocytochemistry
immunofluorescence

immunohistochemistry

microarray

western blot
Anti-β-Catenin−Cy3 antibody, Mouse monoclonal, clone 15B8, purified from hybridoma cell culture,
Reactividad de especies
bovine, canine, chicken, human
Aplicación
immunofluorescence
Monoclonal Anti-β-Catenin antibody produced in mouse, clone 6F9, ascites fluid,
Reactividad de especies
bovine, canine, chicken, human
Aplicación
immunofluorescence
microarray

western blot
Anti-CTNNB1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry

western blot
Anti-CTNNB1 (Ab-33) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
immunofluorescence
immunohistochemistry

western blot

Proteins

Referencia del producto
Descripción
Especie
Catenin β, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human CTNNB1,
Especie
human
MISSION® esiRNA, targeting mouse Ctnnb1,
Especie
mouse