Saltar al contenido
Merck

CTLA4

cytotoxic T-lymphocyte-associated protein 4

Sinónimos:
CD, CD152, CELIAC3, CTLA-4, GRD4, GSE, IDDM12
Especie:
Human CTLA4 (1493), Mouse Ctla4 (12477), Rat Ctla4 (63835), Domestic Rabbit CTLA4 (100009412), domestic guinea pig Ctla4 (100725760), naked mole-rat Ctla4 (101722788), chicken CTLA4 (424106), domestic cat CTLA4 (493743), cow CTLA4 (281732), dog CTLA4 (403696)
ID UniProtKB:
P16410, A0N1S0, E9PDH0, O95653, Q0PP65, Q52MC1, Q53TD5, Q5S005
ID del gen:
  • Human(1493) Summary: This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. [provided by RefSeq, Jul 2008]
  • Mouse(12477) cytotoxic T-lymphocyte-associated protein 4
  • Rat(63835) cytotoxic T-lymphocyte-associated protein 4
  • Domestic Rabbit(100009412) cytotoxic T-lymphocyte-associated protein 4
  • domestic guinea pig(100725760) cytotoxic T-lymphocyte-associated protein 4
  • naked mole-rat(101722788) cytotoxic T-lymphocyte-associated protein 4
  • chicken(424106) cytotoxic T-lymphocyte-associated protein 4
  • domestic cat(493743) cytotoxic T-lymphocyte-associated protein 4
  • cow(281732) cytotoxic T-lymphocyte-associated protein 4
  • dog(403696) cytotoxic T-lymphocyte-associated protein 4

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

ELISA

Referencia del producto
Descripción
Especie
RAB0109
Human CXCL16 ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Especie
human
RAB0110
Mouse CTLA-4 ELISA Kit, for serum, plasma and cell culture supernatant,
Especie
mouse

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
ZRB1783
Anti-CTLA4/CD152 Antibody, clone 1D10 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human, monkey
Aplicación
affinity binding assay
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
C9979
Monoclonal Anti-CD152 antibody produced in mouse, ~1 mg/mL, clone AS32, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
neutralization
western blot

Proteins

Referencia del producto
Descripción
Especie
SRP8051
CD152 (human): FC (human) (non-lytic), recombinant, expressed in CHO cells, ≥98% (SDS-PAGE),
Especie
human
C4483
CD152/Fc Chimera, Cytolytic from mouse, recombinant, expressed in NS.1 cells, buffered aqueous solution,
Especie
mouse

esiRNA

Referencia del producto
Descripción
Especie
EHU124981
MISSION® esiRNA, targeting human CTLA4,
Especie
human