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Merck

CSH1

chorionic somatomammotropin hormone 1 (placental lactogen)

Sinónimos:
CS-1, CSA, CSMT, PL, hCS-A
Especie:
Human CSH1 (1442)
ID UniProtKB:
P01243, Q0VDB1, Q14407
ID del gen:
  • Human(1442) Summary: The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones and plays an important role in growth control. The gene is located at the growth hormone locus on chromosome 17 along with four other related genes in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed mainly in the placenta and utilizes multiple transcription initiation sites. Expression of the identical mature proteins for chorionic somatomammotropin hormones 1 and 2 is upregulated during development, although the ratio of 1 to 2 increases by term. Mutations in this gene result in placental lactogen deficiency and Silver-Russell syndrome. [provided by RefSeq, Jul 2008]

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
HPA043715
Anti-CSH1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
AV40350
Anti-CSH1 antibody produced in rabbit, IgG fraction of antiserum,
Reactividad de especies
dog, guinea pig, human, mouse, rabbit, rat
Aplicación
immunohistochemistry
western blot

esiRNA

Referencia del producto
Descripción
Especie
EHU128341
MISSION® esiRNA, targeting human GH2,
Especie
human