CFTR
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
Sinónimos:
ABC35, ABCC7, CF, CFTR/MRP, MRP7, TNR-CFTR, dJ760C5.1
Especie:
Human CFTR (1080), Mouse Cftr (12638), Rat Cftr (24255), Zebrafish cftr (559080), chicken CFTR (100049619), dog CFTR (492302), domestic cat CFTR (492308), cow CFTR (281067), Horse CFTR (100071259), naked mole-rat Cftr (101709472) ...Más
ID UniProtKB:
ID del gen:
- Human(1080) Summary: This gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily that is involved in multi-drug resistance. The encoded protein functions as a chloride channel and controls the regulation of other transport pathways. Mutations in this gene are associated with the autosomal recessive disorders cystic fibrosis and congenital bilateral aplasia of the vas deferens. Alternatively spliced transcript variants have been described, many of which result from mutations in this gene. [provided by RefSeq, Jul 2008]
- Mouse(12638) cystic fibrosis transmembrane conductance regulator
- Rat(24255) cystic fibrosis transmembrane conductance regulator
- Zebrafish(559080) cystic fibrosis transmembrane conductance regulator, ATP-binding cassette (sub-family C, member 7)
- chicken(100049619) cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
- dog(492302) cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
- domestic cat(492308) cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
- cow(281067) cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
- Horse(100071259) cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
- naked mole-rat(101709472) cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
- domestic guinea pig(100135647) cystic fibrosis transmembrane conductance regulator homolog
- domestic guinea pig(100719898) cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
- sheep(443347) cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
- Domestic Rabbit(100009471) cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
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Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-CFTR antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Anti-CFTR Antibody, clone MM13-4 ZooMAb® Mouse Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human, monkey, porcine
Aplicación
flow cytometry
immunocytochemistry
western blot
immunocytochemistry
western blot
Anti-CFTR antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-CFTR antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
immunohistochemistry