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Merck

CDKN1B

cyclin-dependent kinase inhibitor 1B (p27, Kip1)

Sinónimos:
CDKN4, KIP1, MEN1B, MEN4, P27KIP1
Especie:
ID UniProtKB:
ID del gen:
  • Human(1027) Summary: This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. [provided by RefSeq, Jul 2008]
  • Mouse(12576) cyclin-dependent kinase inhibitor 1B
  • Rat(83571) cyclin-dependent kinase inhibitor 1B
  • chicken(374106) cyclin-dependent kinase inhibitor 1B (p27, Kip1)
  • dog(403429) cyclin-dependent kinase inhibitor 1B (p27, Kip1)
  • cow(512613) cyclin-dependent kinase inhibitor 1B (p27, Kip1)
  • domestic cat(493958) cyclin-dependent kinase inhibitor 1B (p27, Kip1)
  • chicken(769872) cyclin-dependent kinase inhibitor 1B (p27, Kip1)
  • naked mole-rat(101698721) cyclin-dependent kinase inhibitor 1B (p27, Kip1)
  • domestic guinea pig(100729359) cyclin-dependent kinase inhibitor 1B (p27, Kip1)
  • sheep(100127219) cyclin-dependent kinase inhibitor 1B (p27, Kip1)
  • Domestic Rabbit(100009037) cyclin-dependent kinase inhibitor 1B (p27, Kip1)

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-CDKN1B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunofluorescence
western blot
Anti-p27 KIP1 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
immunohistochemistry

western blot
Anti-p27Kip1antibody, Rabbit Monoclonal, recombinant, expressed in HEK 293 cells, clone RM302, purified immunoglobulin,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
Anti-CDKN1B (Ab-10) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot
Anti-p27 KIP1 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human
Aplicación
ELISA
western blot

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
Roscovitine, ≥98% (TLC),
Especie
human, mouse, rat
Olomoucine, ≥98% (HPLC),
Especie
human, rat

Proteins

Referencia del producto
Descripción
Especie
p27KIP1, GST tagged human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Cdkn1b,
Especie
mouse
MISSION® esiRNA, targeting human CDKN1B,
Especie
human