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Merck

CDK2

cyclin-dependent kinase 2

Sinónimos:
p33(CDK2)
Especie:
ID UniProtKB:
ID del gen:
  • Human(1017) Summary: The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by its protein phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported. [provided by RefSeq, Jul 2008]
  • Mouse(12566) cyclin-dependent kinase 2
  • Rat(362817) cyclin dependent kinase 2
  • Zebrafish(406715) cyclin-dependent kinase 2
  • cow(519217) cyclin-dependent kinase 2
  • chicken(100529062) cyclin-dependent kinase 2
  • dog(606931) cyclin-dependent kinase 2
  • domestic cat(101093368) cyclin-dependent kinase 2
  • domestic guinea pig(100714324) cyclin-dependent kinase 2
  • naked mole-rat(101725353) cyclin-dependent kinase 2
  • Goat(100860751) cyclin-dependent kinase 2
  • sheep(100216433) cyclin-dependent kinase 2
  • Domestic Rabbit(100134865) cyclin-dependent kinase 2

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Monoclonal Anti-CDK2 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL7990, purified immunoglobulin, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
Anti-phospho-CDK2 (pThr160) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot
Anti-CDK2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunofluorescence
Anti-phospho-CDK1/CDC2 (pThr14) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
western blot
Anti-Phospho-CDK2-T160 antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
Piceatannol, powder,
Especie
human
Tyrphostin 23, ≥98%,
Especie
human
NU2058, >98% (HPLC),
Especie
human
6-O-Methylguanine, 97%,
Especie
human
Tyrphostin 51, ≥98%,
Especie
human

Proteins

Referencia del producto
Descripción
Especie
CDK2, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Especie
human
CDK2/Cyclin A2, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Especie
human
CDK2/CyclinE1, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Especie
human
CDK2/CyclinA1, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Cdk2,
Especie
mouse
MISSION® esiRNA, targeting human CDK2,
Especie
human