CD97
CD97 molecule
Sinónimos:
TM7LN1
Especie:
Human CD97 (976), Mouse Cd97 (26364), Rat Cd97 (361383), naked mole-rat Cd97 (101709277), domestic guinea pig Cd97 (100719369), sheep CD97 (101122596), dog CD97 (484904), cow CD97 (338066), domestic cat CD97 (101097302)
ID UniProtKB:
ID del gen:
- Human(976) Summary: This gene encodes a member of the EGF-TM7 subfamily of adhesion G protein-coupled receptors, which mediate cell-cell interactions. These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit, which associate at the cell surface as a receptor complex. The encoded protein may play a role in cell adhesion as well as leukocyte recruitment, activation and migration, and contains multiple extracellular EGF-like repeats which mediate binding to chondroitin sulfate and the cell surface complement regulatory protein CD55. Expression of this gene may play a role in the progression of several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms with 3 to 5 EGF-like repeats have been observed for this gene. This gene is found in a cluster with other EGF-TM7 genes on the short arm of chromosome 19. [provided by RefSeq, Jun 2011]
- Mouse(26364) CD97 antigen
- Rat(361383) CD97 molecule
- naked mole-rat(101709277) CD97 molecule
- domestic guinea pig(100719369) CD97 molecule
- sheep(101122596) CD97 molecule
- dog(484904) CD97 molecule
- cow(338066) CD97 molecule
- domestic cat(101097302) CD97 molecule
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