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Merck

CAMKK2

calcium/calmodulin-dependent protein kinase kinase 2, beta

Sinónimos:
CAMKK, CAMKKB
Especie:
ID UniProtKB:
ID del gen:
  • Human(10645) Summary: The product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. The major isoform of this gene plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Protein products of this gene also phosphorylate AMP-activated protein kinase (AMPK). This gene has its strongest expression in the brain and influences signalling cascades involved with learning and memory, neuronal differentiation and migration, neurite outgrowth, and synapse formation. Alternative splicing results in multiple transcript variants encoding distinct isoforms. The identified isoforms differ in their ability to undergo autophosphorylation and to phosphorylate downstream kinases. [provided by RefSeq, Jul 2012]
  • Mouse(207565) calcium/calmodulin-dependent protein kinase kinase 2, beta
  • Rat(83506) calcium/calmodulin-dependent protein kinase kinase 2, beta
  • naked mole-rat(101723556) calcium/calmodulin-dependent protein kinase kinase 2, beta
  • domestic guinea pig(100716041) calcium/calmodulin-dependent protein kinase kinase 2, beta
  • sheep(101103267) calcium/calmodulin-dependent protein kinase kinase 2, beta
  • chicken(396405) calcium/calmodulin-dependent protein kinase kinase 2, beta
  • dog(486263) calcium/calmodulin-dependent protein kinase kinase 2, beta
  • cow(509084) calcium/calmodulin-dependent protein kinase kinase 2, beta
  • domestic cat(101097674) calcium/calmodulin-dependent protein kinase kinase 2, beta

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-CAMKK2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry

western blot
Anti-CAMKK2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry

western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human CAMKK2,
Especie
human
MISSION® esiRNA, targeting mouse Camkk2,
Especie
mouse