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Merck

CACNA2D4

calcium channel, voltage-dependent, alpha 2/delta subunit 4

Sinónimos:
RCD4
Especie:
ID UniProtKB:
ID del gen:
  • Human(93589) Summary: This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]
  • Mouse(319734) calcium channel, voltage-dependent, alpha 2/delta subunit 4
  • Rat(312668) calcium channel, voltage-dependent, alpha 2/delta subunit 4
  • chicken(100858946) calcium channel, voltage-dependent, alpha 2/delta subunit 4
  • domestic cat(101095834) calcium channel, voltage-dependent, alpha 2/delta subunit 4
  • cow(784075) calcium channel, voltage-dependent, alpha 2/delta subunit 4
  • Horse(100630648) calcium channel, voltage-dependent, alpha 2/delta subunit 4
  • dog(477733) calcium channel, voltage-dependent, alpha 2/delta subunit 4
  • sheep(101116306) calcium channel, voltage-dependent, alpha 2/delta subunit 4
  • domestic guinea pig(100716046) calcium channel, voltage-dependent, alpha 2/delta subunit 4
  • naked mole-rat(101705589) calcium channel, voltage-dependent, alpha 2/delta subunit 4

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Small Molecule - Allosteric Modulator

Referencia del producto
Descripción
Especie
Gabapentin, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Gabapentin solution, 10 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Especie
human
Gabapentin, Pharmaceutical Secondary Standard; Certified Reference Material,
Especie
human
Pregabalin, European Pharmacopoeia (EP) Reference Standard,
Especie
human
Gabapentin, European Pharmacopoeia (EP) Reference Standard,
Especie
human

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-CACNA2D4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry

Small Molecule - Blocker

Referencia del producto
Descripción
Especie
Bepridil hydrochloride, powder,
Especie
human
Terodiline hydrochloride, ≥98% (HPLC), solid,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human CACNA2D4,
Especie
human