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Merck

CACNA1S

calcium channel, voltage-dependent, L type, alpha 1S subunit

Sinónimos:
CACNL1A3, CCHL1A3, Cav1.1, HOKPP, HOKPP1, MHS5, TTPP1, hypoPP
Especie:
ID UniProtKB:
ID del gen:
  • Human(779) Summary: This gene encodes one of the five subunits of the slowly inactivating L-type voltage-dependent calcium channel in skeletal muscle cells. Mutations in this gene have been associated with hypokalemic periodic paralysis, thyrotoxic periodic paralysis and malignant hyperthermia susceptibility. [provided by RefSeq, Jul 2008]
  • Mouse(12292) calcium channel, voltage-dependent, L type, alpha 1S subunit
  • Rat(682930) calcium channel, voltage-dependent, L type, alpha 1S subunit
  • chicken(395985) calcium channel, voltage-dependent, L type, alpha 1S subunit
  • domestic cat(654399) calcium channel, voltage-dependent, L type, alpha 1S subunit
  • cow(100337204) calcium channel, voltage-dependent, L type, alpha 1S subunit
  • Horse(100034092) calcium channel, voltage-dependent, L type, alpha 1S subunit
  • dog(490244) calcium channel, voltage-dependent, L type, alpha 1S subunit
  • sheep(101108767) calcium channel, voltage-dependent, L type, alpha 1S subunit
  • Domestic Rabbit(100009585) calcium channel, voltage-dependent, L type, alpha 1S subunit
  • domestic guinea pig(100734741) calcium channel, voltage-dependent, L type, alpha 1S subunit
  • naked mole-rat(101726232) calcium channel, voltage-dependent, L type, alpha 1S subunit

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Small Molecule - Allosteric Modulator

Referencia del producto
Descripción
Especie
Gabapentin, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Gabapentin solution, 10 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Especie
human
Gabapentin, Pharmaceutical Secondary Standard; Certified Reference Material,
Especie
human
Pregabalin, European Pharmacopoeia (EP) Reference Standard,
Especie
human
Gabapentin, European Pharmacopoeia (EP) Reference Standard,
Especie
human

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-CACNA1S antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Anti-CACNA1S antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Monoclonal Anti-Dihydropyridine Receptor (α1 Subunit) antibody produced in mouse, clone 1A, buffered aqueous solution,
Reactividad de especies
guinea pig, human, mouse, rabbit, rat
Aplicación
immunohistochemistry
immunoprecipitation (IP)

western blot

Small Molecule - Blocker

Referencia del producto
Descripción
Especie
Amlodipine besylate, ≥98% (HPLC),
Especie
human
Amlodipine besylate, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Nicardipine hydrochloride, powder, ≥98%,
Especie
human
(+)-cis-Diltiazem hydrochloride, ≥99% (HPLC),
Especie
human
Nicardipine hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human CACNA1S,
Especie
human
MISSION® esiRNA, targeting mouse Cacna1s,
Especie
mouse
MISSION® esiRNA, targeting mouse Cacna1e,
Especie
mouse
MISSION® esiRNA, targeting human CACNA1E,
Especie
human