CACNA1C
calcium channel, voltage-dependent, L type, alpha 1C subunit
Sinónimos:
CACH2, CACN2, CACNL1A1, CCHL1A1, CaV1.2, LQT8, TS
Especie:
Human CACNA1C (775), Mouse Cacna1c (12288), Rat Cacna1c (24239), Zebrafish cacna1c (170581), cow CACNA1C (408015), Horse CACNA1C (100049924), chicken CACNA1C (395891), domestic cat CACNA1C (101082923), dog CACNA1C (403516), naked mole-rat Cacna1c (101717129) ...Más
ID UniProtKB:
ID del gen:
- Human(775) Summary: This gene encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. There are multiple isoforms of each of these proteins, either encoded by different genes or the result of alternative splicing of transcripts. The protein encoded by this gene binds to and is inhibited by dihydropyridine. Alternative splicing results in many transcript variants encoding different proteins. Some of the predicted proteins may not produce functional ion channel subunits. [provided by RefSeq, Oct 2012]
- Mouse(12288) calcium channel, voltage-dependent, L type, alpha 1C subunit
- Rat(24239) calcium channel, voltage-dependent, L type, alpha 1C subunit
- Zebrafish(170581) calcium channel, voltage-dependent, L type, alpha 1C subunit
- cow(408015) calcium channel, voltage-dependent, L type, alpha 1C subunit
- Horse(100049924) calcium channel, voltage-dependent, L type, alpha 1C subunit
- chicken(395891) calcium channel, voltage-dependent, L type, alpha 1C subunit
- domestic cat(101082923) calcium channel, voltage-dependent, L type, alpha 1C subunit
- dog(403516) calcium channel, voltage-dependent, L type, alpha 1C subunit
- naked mole-rat(101717129) calcium channel, voltage-dependent, L type, alpha 1C subunit
- domestic guinea pig(100135490) calcium channel, voltage-dependent, L type, alpha 1C subunit
- Goat(100861292) calcium channel, voltage-dependent, L type, alpha 1C subunit
- sheep(101116562) calcium channel, voltage-dependent, L type, alpha 1C subunit
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Small Molecule - Allosteric Modulator
Referencia del producto
Descripción
Especie
Gabapentin solution, 10 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Especie
human
Small Molecule - Antagonist
Referencia del producto
Descripción
Especie
Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-Calcium Channel (α1C Subunit) (L-type of Voltage-gated Ca2+ Channel) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rabbit, rat
Aplicación
immunohistochemistry
western blot
western blot
Anti-Calcium Channel (Cardiac α1C Subunit) (L-type of Voltage-gated Ca2+ Channel) antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Reactividad de especies
rabbit, rat
Aplicación
immunoprecipitation (IP)
western blot
western blot
Anti-Calcium Channel (α1 Subunit), Pan antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Reactividad de especies
mouse, rat
Aplicación
immunohistochemistry
western blot
western blot
Anti-Calcium Channel CaV1.2 (human) antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Reactividad de especies
human, mouse, rat
Aplicación
immunocytochemistry
western blot
western blot
Small Molecule - Blocker
Referencia del producto
Descripción
Especie
Amlodipine besylate, Pharmaceutical Secondary Standard; Certified Reference Material,
Especie
human