BACE1
beta-site APP-cleaving enzyme 1
Sinónimos:
ASP2, BACE, HSPC104
Especie:
Human BACE1 (23621), Mouse Bace1 (23821), Rat Bace1 (29392), Zebrafish bace1 (403005), cow BACE1 (614333), Horse BACE1 (100071137), domestic cat BACE1 (101086840), dog BACE1 (489390), chicken BACE1 (419768), sheep BACE1 (101119667) ...Más
ID UniProtKB:
ID del gen:
- Human(23621) Summary: Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, May 2011]
- Mouse(23821) beta-site APP cleaving enzyme 1
- Rat(29392) beta-site APP cleaving enzyme 1
- Zebrafish(403005) beta-site APP-cleaving enzyme 1
- cow(614333) beta-site APP-cleaving enzyme 1
- Horse(100071137) beta-site APP-cleaving enzyme 1
- domestic cat(101086840) beta-site APP-cleaving enzyme 1
- dog(489390) beta-site APP-cleaving enzyme 1
- chicken(419768) beta-site APP-cleaving enzyme 1
- sheep(101119667) beta-site APP-cleaving enzyme 1
- Domestic Rabbit(100343442) beta-site APP-cleaving enzyme 1
- naked mole-rat(101701890) beta-site APP-cleaving enzyme 1
- domestic guinea pig(100135485) beta-site APP cleaving enzyme 1
Custom & Knockdown Gene Products
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Custom Gene Products
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ELISA
Referencia del producto
Descripción
Especie
Activity Assay
Referencia del producto
Descripción
Especie
β-Secretase (BACE1) Activity Detection Kit (Fluorescent), 1 kit sufficient for 250 reactions,
Especie
human
Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-BACE 1, N-Terminus (46-62) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
human
Aplicación
western blot
Anti-BACE 1, C-Terminus (485-501) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
human
Aplicación
microarray
western blot
western blot
Anti-BACE1 Antibody, clone 7C5T7, Rabbit Monoclonal, ,
Reactividad de especies
human, rat
Aplicación
western blot
Anti-BACE antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Reactividad de especies
human, mouse
Aplicación
ELISA
immunocytochemistry
immunofluorescence
immunohistochemistry
western blot
immunocytochemistry
immunofluorescence
immunohistochemistry
western blot
Small Molecule - Inhibitor
Kits
Referencia del producto
Descripción
Especie
β-Secretase (BACE1) Activity Detection Kit (Fluorescent), 1 kit sufficient for 250 reactions,
Especie
human
Proteins
Referencia del producto
Descripción
Especie
β-Secretase human, recombinant, expressed in HEK 293 cells (C-terminal FLAG tagged), extracellular domain, ≥10,000 units/mg protein, ≥90% (SDS-PAGE), buffered aqueous solution,
Especie
human